Evidence map›Paper›PMID 42367738›Full record

ArticleBiophysics reports2026

Structural basis for the ion selectivity of potassium-chloride cotransporter KCC4 revealed by cryo-EM titration.

Yuan Xie, Binming Han, Xin Tao, Fangjun Song, Cheng Zhao, Eric Delpire, Jingyuan Li, Shan Wu, Jiangtao Guo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuan Xie *Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
Binming Han *School of Physics, Zhejiang University, Hangzhou 310058, China.
Xin Tao *State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan 430062, China.
Fangjun SongDepartment of Biophysics and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
Cheng ZhaoDepartment of Biophysics and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
Eric DelpireDepartment of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Jingyuan LiSchool of Physics, Zhejiang University, Hangzhou 310058, China.
Shan WuState Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan 430062, China.
Jiangtao GuoDepartment of Biophysics and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Potassium-chloride cotransporters KCCs mediate the coupled, electroneutral cotransport of K

Indexed as

Cryo-EM titrationIons cotransportIons selectivityKCC4Molecular dynamic simulation

Identifiers

PMID42367738
PMCPMC13294203

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.