ArticleIJID regions2026
Distribution and antibiotic resistance profiles of uropathogens at Madan Bhandari Hospital, Nepal: Focus on multidrug and extensively drug-resistant strains.
Article in IJID regions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: This study aimed to determine the distribution and antibiotic resistance patterns of uropathogens, emphasizing MDR and XDR strains, at a secondary care hospital to fill gaps in community-linked resistance data not captured by tertiary centers. Design or Methods: A total of 2734 urine cultures collected between June 2024 and April 2025 at Madan Bhandari Hospital were analyzed. Isolates were identified on Blood and MacConkey Agar, and antibiotic susceptibility testing was performed using the modified Kirby-Bauer disk diffusion method. MDR/XDR classification followed European Centre for Disease Prevention and Control/Centers for Disease Control and Prevention criteria. Results: Significant growth was found in 209 samples (7.64%), dominated by Conclusion: The high prevalence of MDR/XDR uropathogens and resistance to first-line antibiotics underscores the importance of incorporating local surveillance data into treatment protocols. Conducting this study in a secondary hospital provides a clearer representation of community-linked resistance patterns, complementing tertiary hospital data and informing targeted antimicrobial stewardship strategies in Nepal.
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