ArticleThe journal of physical chemistry letters2026
Spiking without Resets: Continuous Integrate-and-Fire Dynamics in Neuronal Circuits.
Article in The journal of physical chemistry letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The leaky integrate-and-fire paradigm is widely used to describe spiking dynamics in biological and artificial neurons. However, its implementation typically relies on explicit reset rules or intrinsic mechanisms involving negative differential resistance. Here we address the question: Can spike-like behavior emerge within a fully continuous dynamical framework without such ingredients?. We study a minimal resistive-capacitive circuit coupled to a conductance-activated quasi-linear memristor characterized by a single intrinsic relaxation time scale and an internal state variable. We demonstrate that spiking arises from the nonlinear coupling of the state variable and its voltage-dependent equilibrium value. Rather than being governed by a minimum transition slope in the static current-voltage characteristics, the onset of spiking does not exhibit sharp parametric thresholds but instead depends sensitively on the excitation frequency.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.