Evidence map›Paper›PMID 42366732›Full record

ArticleTransboundary and emerging diseases2026

Development of a Serotyping Scheme for Streptococcus pasteurianus: An Underreported Zoonotic Pathogen.

Shuoyue Wang, Xinchun Li, Chenxu Zheng, Jinlu Zhu, Anusak Kerdsin, Zongfu Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transboundary and emerging diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuoyue WangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210014, China, njau.edu.cn.
Xinchun LiMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210014, China, njau.edu.cn.
Chenxu ZhengMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210014, China, njau.edu.cn.
Jinlu ZhuMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210014, China, njau.edu.cn.ORCID https://orcid.org/0009-0003-4342-4639
Anusak KerdsinFaculty of Public Health, Kasetsart University, Chalermphrakiat Sakon Nakhon Province Campus, Sakon Nakhon, 47000, Thailand, ku.ac.th.ORCID https://orcid.org/0000-0003-1055-3656
Zongfu WuMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210014, China, njau.edu.cn.ORCID https://orcid.org/0000-0002-6048-6829

Funding

National Key Research and Development Program of China 2023YFD1800503
6 · The paper itself

Abstract

Streptococcus pasteurianus is an opportunistic and underreported zoonotic pathogen capable of causing severe infections in both humans and animals, and it is also an etiological agent of swine streptococcosis. Despite its clinical and veterinary relevance, no systematic serotyping scheme has previously been established for this species. In this study, six representative strains harboring distinct cps gene clusters were selected for antiserum production, and agglutination assays identified five serotypes, designated serotypes 1a, 1b, 2, 3, and 4. Based on serotype-specific variation within the cps gene cluster, a multiplex PCR (mPCR) serotyping assay was subsequently developed and evaluated using 35 S. pasteurianus strains, including 14 pig isolates, 19 human isolates, and two cattle isolates. Serotype assignments obtained by mPCR were fully concordant with those determined by agglutination assays using rabbit antisera. In addition, transmission electron microscopy (TEM) revealed a visible capsular layer surrounding representative strains of each serotype. Collectively, these findings establish a robust serotyping framework for S. pasteurianus. The mPCR serotyping assay provides a valuable tool for future epidemiological studies, enhances diagnostic capability, and supports improved surveillance and control of S. pasteurianus infections.

Indexed as

SerotypingStreptococcal InfectionsStreptococcusAnimalsCattleHumansMultiplex Polymerase Chain ReactionSwineZoonosescapsular polysaccharidesserotypeStreptococcus pasteurianus

Identifiers

PMID42366732
PMCPMC13311317

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.