Evidence map›Paper›PMID 42366515›Full record

ArticleGut microbes2026

Identification of human DP8α regulatory T cell sub-populations reactive to health-associated anti-inflammatory gut commensals.

Margaux de Seilhac, Margaux Verdon, Lucas Goisnard, Aurore Duquenoy, Nathalie Corvaia, Emilie Plantamura, Nicolas Lapaque, Fabienne Beguet-Crespel, Bastien Laperrousaz, Joel Doré and 2 more

Abstract read
In one paragraph

Article in Gut microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Margaux de SeilhacNantes Université, Univ Angers, INSERM, CNRS, Immunology and New Concepts in ImmunoTherapy, INCIT,
UMR 1302, Nantes, France.
Margaux VerdonNantes Université, Univ Angers, INSERM, CNRS, Immunology and New Concepts in ImmunoTherapy, INCIT,
UMR 1302, Nantes, France.
Lucas GoisnardNantes Université, Univ Angers, INSERM, CNRS, Immunology and New Concepts in ImmunoTherapy, INCIT,
UMR 1302, Nantes, France.
Aurore DuquenoyMaaT Pharma, Lyon, France.
Nathalie CorvaiaMaaT Pharma, Lyon, France.
Emilie PlantamuraMaaT Pharma, Lyon, France.
Nicolas LapaqueMicalis Institute, INRAE, AgroParisTech, University Paris-Saclay, Jouy-en-Josas, France.
Fabienne Beguet-CrespelMicalis Institute, INRAE, AgroParisTech, University Paris-Saclay, Jouy-en-Josas, France.
Bastien LaperrousazMaaT Pharma, Lyon, France.
Joel DoréMicalis Institute, INRAE, AgroParisTech, University Paris-Saclay, Jouy-en-Josas, France.ORCID 0000-0002-8756-0718
Frédéric AltareNantes Université, Univ Angers, INSERM, CNRS, Immunology and New Concepts in ImmunoTherapy, INCIT,
UMR 1302, Nantes, France.
Emmanuelle GodefroyNantes Université, Univ Angers, INSERM, CNRS, Immunology and New Concepts in ImmunoTherapy, INCIT,
UMR 1302, Nantes, France.ORCID 0000-0002-4981-6639

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the role of gut microbiota in health has been demonstrated, deciphering the involvement of individual bacterial species in diseases with unmet clinical needs represents a major research interest. Over the last decade, DP8α regulatory T cells (Tregs) have been identified to respond to

Indexed as

Gastrointestinal MicrobiomeT-Lymphocytes, RegulatoryAkkermansiaHumansInflammatory Bowel DiseasesLymphocyte ActivationVerrucomicrobiaAkkermansia muciniphilaBlautiadendritic cellsFaecalibacterium duncaniaeGut microbiotahuman gut microbiota-specific Tregsimmune regulationregulatory T cellsRoseburia intestinalis

Identifiers

PMID42366515
PMCPMC13321884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.