ReviewSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi2026
[Mechanisms and applications of magnesium ion-regulated stem cell functions in promoting tendon-bone interface healing].
Review in Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
This review systematically examines the mechanisms and recent research progress of magnesium ions in promoting tendon-bone interface repair by regulating stem cell functions. Firstly, the analysis indicates that magnesium ions synergistically regulate stem cell proliferation, migration, and multidirectional differentiation through multiple signaling pathways, while simultaneously promoting angiogenesis and optimizing the immune microenvironment. Subsequently, a summary of existing research findings confirms that magnesium-based biodegradable biomaterials demonstrate favorable tissue repair-promoting effects in animal experiments. Finally, this article proposes that, given the spatiotemporal sequential characteristics of magnesium ion regulation on stem cells and the healing microenvironment, future research should focus on developing novel smart materials capable of precisely controlling magnesium ion release to match the healing process, thereby advancing its clinical translation and precision medicine applications in the field of tendon-bone repair.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.