Evidence map›Paper›PMID 42366412›Full record

ReviewCost effectiveness and resource allocation : C/E2026

Extended cost-effectiveness analysis in global health systems: a scoping review of geographic gaps and research trends.

Saman Najafi, Mahmoud Nekoei Moghadam, Mohammad Reza Amiresmaili, Mohsen Barouni, Ali Akbar Haqhdoost, Mohammad Jafari Sirizi, Reza Goudarzi

Abstract readReview
In one paragraph

Review in Cost effectiveness and resource allocation : C/E, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Saman NajafiDepartment of Health Management and Policy and Economic, Faculty of Management and Medical Information Sciences, Kerman University of Medical Sciences, Kerman, Iran.
Mahmoud Nekoei MoghadamHealth in Disasters and Emergencies Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Mohammad Reza AmiresmailiHealth in Disasters and Emergencies Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Mohsen BarouniHealth Services Management Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Ali Akbar HaqhdoostHIV/STI Surveillance Research Center and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Mohammad Jafari SiriziIran Insurance Health Kerman Office, Kerman, Iran.
Reza GoudarziHealth Services Management Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran. rgoudarzi@yahoo.com.ORCID http://orcid.org/0000-0003-4399-3498

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtended Cost-Effectiveness Analysis (ECEA) extends conventional cost-effectiveness analysis by incorporating financial risk protection (FRP) and examining the distribution of health and economic outcomes across socioeconomic groups. This scoping review aimed to map the application of ECEA in health-sector studies, identify methodological patterns, and explore geographic and thematic research gaps.

methodsA scoping review was conducted in accordance with PRISMA 2020 guidelines. Searches were performed on 29 October 2025 in PubMed, Scopus, Web of Science, ProQuest, and Google Scholar. Studies published between 2000 and 2025 that applied ECEA to evaluate health interventions were eligible for inclusion. Data were extracted on intervention characteristics, analytical approaches, equity measures, and FRP outcomes and were synthesized narratively.

resultsA total of 1,955 records were identified, of which 19 studies met the inclusion criteria. Most studies were conducted in low- and middle-income countries, particularly in Asia and Africa. The included studies primarily evaluated vaccination programs, taxation policies on harmful products, publicly financed health services, and maternal and child health interventions. Financial Risk Protection (FRP) outcomes were most commonly reported as reductions in out-of-pocket expenditures, catastrophic health expenditures averted, and poverty cases averted. Across studies, ECEA was predominantly used to assess the distribution of health and financial outcomes across socioeconomic groups, with outcomes commonly reported by income quintiles.

conclusionECEA applications remain limited and are predominantly concentrated in low- and middle-income countries, particularly within preventive and fiscal health interventions. The reviewed evidence suggests that ECEA provides a useful framework for assessing both health outcomes and financial risk protection across socioeconomic groups. Future research should expand ECEA applications to underrepresented settings and promote greater methodological standardization of equity and FRP measures.

Indexed as

Extended cost-effectiveness analysis (ECEA)Financial risk protection (FRP)Health economicsHealth equityPublic health policyResource allocationScoping review

Identifiers

PMID42366412
PMCPMC13573463

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.