Evidence map›Paper›PMID 42366321›Full record

ArticleSleep & breathing = Schlaf & Atmung2026

Nocturnal hypoxemic burden in obesity hypoventilation syndrome compared to obstructive sleep apnea: a case-control study.

Husam I Alahmadi

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Husam I AlahmadiDepartment of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. halahmadi009@kau.edu.sa.ORCID http://orcid.org/0009-0002-2613-0973

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObesity hypoventilation syndrome (OHS) is a severe consequence of the global obesity epidemic. This study compared the patterns and severity of nocturnal oxygen desaturation in adults with OHS and obstructive sleep apnea (OSA).

methodsThis case-control study conducted at King Abdulaziz University Hospital reviewed polysomnography (PSG) records (2016-2022) of patients with OHS and OSA. The data included demographics, BMI, and indices (apnea-hypopnea index [AHI], baseline/minimum SpO₂, percentage of total sleep time with SpO₂ < 90 percent [T90], total sleep time). GraphPad Prism was used for the analysis. Data were summarized as medians and interquartile ranges (IQR). Mann-Whitney U and Kruskal-Wallis tests with Dunn's test were used to compare groups. Fisher's exact test analyzed categorical variables (p < 0.05). The study was approved by the Ethics Committee.

resultsOf the 199 PSG studies, 15 patients met OHS criteria and 184 had OSA. The OHS group had a higher BMI (50.0 [47.0-55.0] kg m

conclusionDespite similar AHI, OHS is associated with a greater hypoxemic burden than OSA, especially in females. These findings underscore the need to consider both diagnosis and sex in sleep-disordered breathing to develop sex-specific treatment approaches.

Indexed as

HypoxiaObesity Hypoventilation SyndromeSleep Apnea, ObstructiveAdultBody Mass IndexCase-Control StudiesFemaleHumansMaleMiddle AgedPolysomnographyBody Mass Index (BMI)HypoxemiaNocturnal Oxygen DesaturationObesity Hypoventilation SyndromeObstructive Sleep ApneaSleep-Disordered Breathing

Identifiers

PMID42366321

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.