ArticleBrain topography2026
Local Field Potential Recordings Using Deep Brain Stimulation: A Practical Workflow and Open-Source Signal Processing Pipeline.
Article in Brain topography, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
16 authors.
Funding
Abstract
Deep brain stimulation (DBS) systems with electrophysiological recording capabilities offer a unique opportunity to chronically record local field potentials (LFP) from implanted electrodes, enabling real-time monitoring of subcortical neural dynamics and the development of adaptive neuromodulation strategies. However, translating raw LFP into clinically relevant biomarkers remains challenging due to numerous technical considerations. To address this, we share both a practical guide for conducting LFP experiments and BrainWave-DBS, an open-source pipeline that implements the workflow and supports analysis of patient-derived LFP data. The pipeline covers data import, preprocessing, spectral analysis, and visualization, offering a reproducible framework for LFP analysis. Furthermore, we demonstrate the functionality of the pipeline using a representative Parkinson's disease dataset and highlight key technical insights gained through this work. By improving access to neural signal acquisition and analysis, our goal is to foster broader adoption of this technology, which could advance closed-loop neuromodulation of deep brain structures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.