Evidence map›Paper›PMID 42366184›Full record

ArticleSubstance use & misuse2026

Opioid Message Fatigue in the United States: Prevalence and Associations with Stigma and Policy Support.

Alyssa Harrell-Webber, Wan-Lun Chang, Naessiamba Eab-Aggrey, Bruce G Taylor, Phoebe A Lamuda, Harold A Pollack, John A Schneider, Faye S Taxman, Xiaoquan Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Substance use & misuse, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alyssa Harrell-WebberDepartment of Communication, George Mason University, Fairfax, Virginia, USA.ORCID 0009-0005-4919-8374
Wan-Lun ChangDepartment of Communication, George Mason University, Fairfax, Virginia, USA.ORCID 0009-0001-0041-1104
Naessiamba Eab-AggreyDepartment of Communication, George Mason University, Fairfax, Virginia, USA.ORCID 0009-0003-2230-6473
Bruce G TaylorNORC at the University of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-8115-1438
Phoebe A LamudaNORC at the University of Chicago, Chicago, Illinois, USA.
Harold A PollackCrown Family School of Social Work, Policy, and Practice, University of Chicago, Chicago, Illinois, USA.
John A SchneiderCrown Family School of Social Work, Policy, and Practice, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-7870-5639
Faye S TaxmanSchar School of Public Policy, George Mason University, Fairfax, Virginia, USA.ORCID 0000-0001-9530-731X
Xiaoquan ZhaoDepartment of Communication, George Mason University, Fairfax, Virginia, USA.ORCID 0000-0003-0264-6262

Funding

Technical Assistance CoreU2CDA050097 · NIDA · GEORGE MASON UNIVERSITY · PI Todd David Molfenter, Jessica Hulsey Nickel · 2019 to 2026
$37.0M
Survey CoreU2CDA050098 · NIDA · UNIVERSITY OF CHICAGO · PI POLLACK, HAROLD ALEXANDER, SCHNEIDER, JOHN · 2019 to 2019
$17.2M
NIDA NIH HHS U2C DA050097NIDA NIH HHS U2C DA050098
6 · The paper itself

Abstract

backgroundThe opioid crisis has generated widespread public attention and messaging. However, persistent messaging may contribute to message fatigue, i.e., feelings of exhaustion and boredom due to excessive and redundant exposure. This study investigates the prevalence of opioid message fatigue among American adults, its association with individual characteristics, and its connection with opioid use disorder (OUD) stigma and policy support for OUD treatment.

methodA nationally representative cross-sectional sample of U.S. household adults aged 18+ (

resultsOn average, participants reported a moderate level of message fatigue (

conclusionsFuture research should continue to examine the social and policy implications of OUD message fatigue and improve public health communication by anticipating and mitigating message fatigue through strategic planning.

Indexed as

Message fatigueopioid crisisOUDpolicy supportstigma

Identifiers

PMID42366184
PMCPMC13436595

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.