Evidence map›Paper›PMID 42366115›Full record

ArticleEarly intervention in psychiatry2026

Public Health Service Clinical Journeys of Patients With Primary Substance Use Disorders Who Are Subsequently Diagnosed With Non-Affective Psychotic Disorders.

Kevin E K Chai, Elvis Rapoo, Crystal M Y Lee, Peter M McEvoy, Kyran Graham-Schmidt, Daniel Rock, Kim S Betts, Suzanne Robinson, Mathew Coleman

Abstract read
In one paragraph

Article in Early intervention in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kevin E K ChaiSchool of Population Health, Curtin University, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0003-1645-0922
Elvis RapooWestern Australia Country Health Service, Geraldton, Western Australia, Australia.
Crystal M Y LeeSchool of Population Health, Curtin University, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0001-6613-5491
Peter M McEvoySchool of Population Health, Curtin University, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0003-2924-6760
Kyran Graham-SchmidtWestern Australia Department of Health, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0002-7794-6211
Daniel RockWestern Australia Primary Health Alliance, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0001-8758-7905
Kim S BettsSchool of Population Health, Curtin University, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0001-5855-1911
Suzanne RobinsonSchool of Population Health, Curtin University, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0001-5703-6475
Mathew ColemanWestern Australia Country Health Service, Geraldton, Western Australia, Australia.ORCID https://orcid.org/0000-0001-9488-2777

Funding

Digital Health CRC DHCRC-0076
6 · The paper itself

Abstract

introductionPsychosis is a debilitating condition and prompt treatment is a key prognostic factor. Early intervention services aim to provide timely care, but co-occurring substance use disorders (SUDs) complicate treatment, leading to poorer outcomes. This study examined the clinical journey of individuals with SUD who were subsequently diagnosed with a psychotic disorder, focusing on the interval between diagnoses to understand this issue.

methodsPatient pathways were constructed using linked health data (2005-2022) from Western Australia for individuals aged ≥ 18 years with a diagnosis of SUD followed by a primary psychotic disorder. Service events across emergency departments (EDs), inpatient and community mental health services were analysed. Descriptive statistics and subgroup analyses examined variations based on the time between diagnoses, sex, remoteness and socioeconomic status.

resultsAnalysis of 7568 patient pathways revealed a median diagnostic interval of 1.9 years. Initial SUD diagnoses occurred most frequently in inpatient settings (62%), whilst psychoses diagnoses were most common in EDs (46%). Common diagnostic pathways included inpatient to ED (28%) and inpatient to inpatient (24%). Subgroup analyses showed women had a 7-month longer diagnostic interval and six more mental health service events than men. Remoteness and socioeconomic disadvantage correlated with increased diagnosis in inpatient settings and decreased diagnosis in EDs.

conclusionA significant delay between diagnoses is likely associated with poorer outcomes. Integrated service delivery, particularly between EDs and specialised mental health services, is important for early intervention. Patient demographics and geographic location influence diagnostic pathways, suggesting targeted interventions to improve access to prompt, appropriate care.

Indexed as

Psychotic DisordersSubstance-Related DisordersAdolescentAdultCommunity Mental Health ServicesDiagnosis, Dual (Psychiatry)Emergency Service, HospitalFemaleHumansMaleMiddle AgedTreatment DelayWestern AustraliaYoung Adultclinical journeypatient pathwayspsychosissubstance use disorder

Identifiers

PMID42366115
PMCPMC13310655

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.