Evidence map›Paper›PMID 42365519›Full record

Trial reportClinical oral implants research2026

Adjunctive Electrolytic Implant Surface Decontamination in the Reconstructive Surgical Treatment of Peri-Implantitis-A Randomized Clinical Trial.

Erik Regidor, Alberto Ortiz-Vigón, Jessica Berglundh-Gottlieb, Jan Derks, Kostas Bougas

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical oral implants research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erik RegidorPeriodontal and Peri-Implant Related Diseases and Therapies, Arrow Development SL, Bilbao, Spain.ORCID https://orcid.org/0000-0003-3338-6379
Alberto Ortiz-VigónPeriodontal and Peri-Implant Related Diseases and Therapies, Arrow Development SL, Bilbao, Spain.
Jessica Berglundh-GottliebDepartment of Periodontology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0001-8394-7512
Jan DerksDepartment of Periodontology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-1133-6074
Kostas BougasDepartment of Periodontology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0001-7476-0182

Funding

Arrow Development SL (Bilbao, Spain).Nobel Biocare (Kloten, SwitzerlandStraumann Research Grant, Institut Straumann AG (Basel, Switzerland)
6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate the adjunctive effect of electrolytic cleaning in the surgical treatment of peri-implantitis. MATERIALS AND

methodsA total of 40 patients (44 implants) with peri-implantitis-associated intra-bony defects were included in this single-center randomized controlled trial. Surgical decontamination of implant surfaces was initiated by use of a rotating titanium brush. Following random allocation, adjunctive electrolytic cleaning was performed in the test group. Xenogeneic bone substitute and a resorbable collagen membrane were then used in both groups. Clinical parameters including probing pocket depth (PPD), bleeding/suppuration on probing, buccal mucosal recession (REC), and keratinized mucosa were assessed at 6 and 12 months. Radiographic marginal bone levels (MBL) and patient-reported outcomes (PROs) were evaluated at 12 months. The primary outcome was a composite measure including implant survival, complete absence of BoP/SoP, PPD ≤ 5 mm and REC ≤ 1 mm at 12 months.

resultsAt 12 months, no implants were lost. The composite outcome was complete at 27.3% of control and 40.0% of test implants (p = 0.41). Mean PPD reductions were 4.5 ± 2.6 mm (control) and 3.8 ± 2.3 mm (test), while MBL gains were 1.9 ± 2.4 mm and 2.1 ± 2.0 mm, respectively. No significant intergroup differences were observed for any clinical, radiographic or PROs. Post-surgical complications occurred in the test group.

conclusionsClinical, radiographic and patient-reported outcomes of surgical therapy of peri-implantitis were favorable at 12 months. The adjunctive use of electrolytic cleaning provided no added benefit over the use of a rotating titanium brush alone.

trial registrationISRCTN17197337 (ISRCTN).

Indexed as

DecontaminationDental ImplantsElectrolysisPeri-ImplantitisAgedBone SubstitutesFemaleHumansMaleMiddle AgedSurface PropertiesTreatment OutcomeBone SubstitutesDental Implantsbone graftperi‐implant bone defectsperi‐implantitisreconstructive surgical therapy

Identifiers

PMID42365519
PMCPMC13542734

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.