Evidence map›Paper›PMID 42365459›Full record

ReviewCanadian journal of gastroenterology & hepatology2026

Independent Prognosis Prediction of Hepatocellular Carcinoma Using MicroRNA-Based Single and Combined Biomarkers.

Long-Bin Jeng, Wen-Ling Chan, Chiao-Fang Teng

Abstract readReview
In one paragraph

Review in Canadian journal of gastroenterology & hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Long-Bin JengOrgan Transplantation Center, China Medical University Hospital, Taichung, 404, Taiwan, cmu.edu.tw.
Wen-Ling ChanBioinformatics and Medical Engineering, College of Medical and Health Science, Asia University, Taichung, 413, Taiwan, asia.edu.tw.
Chiao-Fang TengOrgan Transplantation Center, China Medical University Hospital, Taichung, 404, Taiwan, cmu.edu.tw.ORCID https://orcid.org/0000-0002-5218-0571

Funding

China Medical University CMU112-ASIA-06China Medical University CMU114-ASIA-03
6 · The paper itself

Abstract

Although there are various treatment modalities available for hepatocellular carcinoma (HCC), HCC is still among the most common causes of cancer-related death globally. Identifying independent biomarkers of poor prognosis in HCC patients remains a critical goal to allow timely intervention and ameliorate patient survival. MicroRNAs (miRNAs), the most widely investigated small noncoding RNAs to date, play a crucial role in regulating the initiation and progression of HCC. The expression of numerous miRNAs is altered in tumor tissues and blood specimens of HCC patients, underscoring their potential as promising prognostic biomarkers. This review offers an exhaustive overview of the current literature examining tissue- and circulation-derived miRNAs as single or combined independent prognostic biomarkers in HCC patients.

Indexed as

Biomarkers, TumorCarcinoma, HepatocellularLiver NeoplasmsMicroRNAsHumansPrognosisBiomarkers, TumorMicroRNAscombinedhepatocellular carcinomaindependent prognostic biomarkermicroRNAsingle

Identifiers

PMID42365459
PMCPMC13310390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.