Evidence map›Paper›PMID 42365423›Full record

ReviewJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2026

A comprehensive review on chemical structure, quality control, pharmacological effects, and structure-activity relationship of saponins from Zhuzishen ().

Min Zeting, X U Qianqian, Shi Mengqiong, Guo Wei, Zhang Jihong, Chen Maohua, X U Jie, H U Huiquan, Zhou Gang, Tang Haiming

Abstract readReview
In one paragraph

Review in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Min ZetingCollege of Medicine and Health Sciences, China Three Gorges University, Yichang 443002, China.
X U QianqianHubei Key Laboratory of Tumor Microenvironment and Immunotherapy, College of Basic Medical Sciences, China Three Gorges University, Yichang 443002, China.
Shi MengqiongHubei Key Laboratory of Tumor Microenvironment and Immunotherapy, College of Basic Medical Sciences, China Three Gorges University, Yichang 443002, China.
Guo WeiChinese Medicine Hospital and Hubei Clinical Research Center for Functional Digestive Diseases of Traditional Chinese Medicine, China Three Gorges University, Yichang 443002, China.
Zhang JihongChinese Medicine Hospital and Hubei Clinical Research Center for Functional Digestive Diseases of Traditional Chinese Medicine, China Three Gorges University, Yichang 443002, China.
Chen MaohuaChinese Medicine Hospital and Hubei Clinical Research Center for Functional Digestive Diseases of Traditional Chinese Medicine, China Three Gorges University, Yichang 443002, China.
X U JieChinese Medicine Hospital and Hubei Clinical Research Center for Functional Digestive Diseases of Traditional Chinese Medicine, China Three Gorges University, Yichang 443002, China.
H U HuiquanChinese Medicine Hospital and Hubei Clinical Research Center for Functional Digestive Diseases of Traditional Chinese Medicine, China Three Gorges University, Yichang 443002, China.
Zhou GangChinese Medicine Hospital and Hubei Clinical Research Center for Functional Digestive Diseases of Traditional Chinese Medicine, China Three Gorges University, Yichang 443002, China.
Tang HaimingCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.

Funding

Hubei Provincial Department of Science and Technology Key Research and Development Big Health Plan Project: Research on the Mechanism and Application of Total Saponins from Zhuzishen (Rhizoma Panacis Majoris), a Traditional Chinese Medicine with Western Hubei Characteristics in Preventing and Treating Non-alcoholic Fatty Hepatitis 2022BCE017Key Traditional Chinese Medicine Project of Hubei Provincial Health Commission: Molecular Mechanism of Total Triterpenoids in Chaenomeles Speciosa Protecting Gastric Mucosa and Promoting Healing of Damaged Gastric Mucosa from Trefoil Factor Family/C-X-C Chemokine Receptor Type 4 Signaling Cascade Study ZY2023Z015Mechanism of Total Triterpenes from Chaenomeles Speciosa in Treating Rheumatoid Arthritis Mediated by Toll-like Receptor 4/Nuclear Factor-κB/NOD-like Receptor Thermal Protein Domain Associated Protein 3 Inflammasome Pathway and Inflammatory Cell Immune Activation 2022CFB357Molecular Mechanism of Total Triterpenoids from Chaenomeles Speciosa in Protecting Gastric Mucosa and Promoting Healing of Damaged Gastric Mucosa 2022CFB427Molecular Mechanism of Total Triterpenoids from Chaenomeles Speciosa in the Treatment of Gastric Cancer Based on Toll-like Receptor 4/Nuclear Factor-κB/NOD-like Receptor Thermal Protein Domain Associated Protein 3 Pathway Activation 2023AFB600Natural Science Foundation Project of Hubei Provincial Department of Science and Technology: Mechanism and Application of Total Triterpenes from Cyclocarya paliurus, a Traditional Chinese Medicine with Western Hubei Characteristics, in Resisting Obesity 2025BCB067Open Foundation of Hubei Key Laboratory of Wudang Characteristic Traditional Chinese Medicine Research: Study on Preparation of Chaenomeles Speciosa Triterpene Hydrogel and Its Effect and Mechanism on Promoting Skin Wound Healing WDCM2022010Open Fund of Traditional Chinese Medicine Clinical Research Center for Functional Digestive System Diseases in Hubei Province: Molecular Mechanism of Jianpi Huazhuo Formula in Treating Intestinal Polyps through Toll-like Receptor 4/Nuclear Factor-κB/NOD-like Receptor Thermal Protein Domain Associated Protein 3 Inflammasome Pathway Mediated Immune Inflammatory Activation SXZ202308Preparation of Qingzhuan Tea Zhen and Its Regulating Effect on Imbalance of Intestinal Microbiota A18-302-a2Research Foundation of Yichang City Science and Technology Bureau: Research on the Mechanism of Chaenomeles Speciosa "Hewei Huashi" in Preventing Non-Steroidal Anti-Inflammatory Drugs Induced Gastric Mucosal Injury Based on microRNA-423-5p/Trefoil Factor/Non-steroidal Anti-inflammatory Drug-activated Gene-1 Pathway A21-2-044Study on the Mechanism of Total Triterpenes from Chaenomeles Speciosa in Clearing Aging Epithelial Cells and Resisting Gastric Aging SXZ202311Zhejiang Basic Public Welfare Research Program: Molecular Mechanism of Saponins from Suanzaoren Hehuan Formula to Treat Depression and Insomnia through Toll-like Receptor 4/Nuclear Factor-κB/NOD-like Receptor Thermal Protein Domain Associated Protein 3 Inflammasome Pathway Mediated Immune Inflammatory Activation LGF21H090002Zhejiang Medical and Health Science and Technology Plan Project: Research on the Lead Compounds of Antidepressant Activity in the She Ethnic Medicine Eupatorium Chinense L. Based on the NOD-like Receptor Thermal Protein Domain Associated Protein 3 Inflammasome Pathway 2022497454
6 · The paper itself

Abstract

Zhuzishen (

Indexed as

Drugs, Chinese HerbalPanaxSaponinsAnimalsHumansMolecular StructureQuality ControlStructure-Activity RelationshipDrugs, Chinese HerbalSaponinspharmacological activitiesquality controlreviewsaponinsstructure-activity relationshipZhuzishen ()

Identifiers

PMID42365423
PMCPMC13266333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.