Evidence map›Paper›PMID 42365415›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2026

Clinical characteristics of acupoint sensitization in patients with essential hypertension: a cross-sectional matched case-control study.

Gong Yu, Hao Xiaomin, Liu Qingguo, Tian Junjian, Liu Yu

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Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Gong YuSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 102400, China.
Hao XiaominDepartment of Acupuncture and Moxibustion, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100000, China.
Liu QingguoSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 102400, China.
Tian JunjianSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 102400, China.
Liu YuDepartment of Medicine, School of Special Education, Beijing Union University, Beijing 100071, China.

Funding

Open Project of National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion: a Study on The Evidence-Based Evaluation of the Acupuncture Therapy of Promoting Blood Circulation and Dispelling Wind in the Treatment of Primary Hypertension NCRCOP2023004Young Faculty and High-Level Project Incubation Program of Beijing Union University: a Study on the Mechanism of Pingchong Jiangni Acupuncture in Regulating the Adenosine 5'-monophosphate-activated Protein Kinase/ Perilipin 2 Lipophagy Signaling Pathway in the Paraventricular Nucleus of Spontaneously Hypertensive Rats ZK30202508
6 · The paper itself

Abstract

objectiveTo observe the characteristics of acupoint sensitization in patients with essential hypertension, analyze the mechanical pain threshold and tenderness threshold of each acupoint, and summarize the clinical characteristics of high-sensitivity acupoints.

methodsThis study employed a cross-sectional matched case-control design and enrolled a total of 448 volunteer participants, including 224 patients with hypertension and 224 healthy controls. The main outcome measures included measuring the mechanical pain threshold and tenderness threshold of 16 highly sensitive acupoints in both hypertensive subjects and healthy controls. The receiver operating characteristic curve method was used to evaluate the sensitivity of each acupoint. Additionally, the rules of mechanical pain threshold, tenderness threshold sensitization rate, and degree of sensitization of each acupoint in hypertension patients were summarized to identify the optimal highly sensitive acupoints related to hypertension. RESUITS: The mechanical pain threshold and tenderness threshold of hypertensive patients were significantly lower than those of healthy subjects, the difference was statistically significant (

conclusionThis study successfully achieved the objective of exploring acupoint sensitization in patients with primary hypertension. Hypertensive patients exhibited significantly lower mechanical pain thresholds and pressure pain thresholds compared to healthy subjects. These findings provide clinical evidence for acupoint selection in acupuncture treatment for primary hypertension.

Indexed as

Acupuncture PointsEssential HypertensionHypertensionAcupuncture TherapyAdultAgedCase-Control StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedPain Thresholdacupoint sensitizationcase-control studiescross-sectional studiesessential hypertensionROC analyses

Identifiers

PMID42365415
PMCPMC13266324

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