Evidence map›Paper›PMID 42365272›Full record

ArticleBMC oral health2026

Efficacy of van Beek headgear activator in adolescents with UARS and hyperdivergent skeletal class II malocclusion: dentofacial morphology, airway, and growth.

Xiaojing Zhang, Xinghao Wang, You Wu, Yufei Wang, Xiaohong Huang, Yawen Zhang, Lingyi Huang, Guohao Chen, Yan Jiang

Abstract read
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Xiaojing Zhang *Department of Stomatology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Xinghao Wang *School of Stomatology, Fujian Medical University, Fuzhou, 350004, China.
You Wu *School of Stomatology, Fujian Medical University, Fuzhou, 350004, China.
Yufei WangSchool of Basic Medical Sciences, Fujian Medical University, Fuzhou, 350122, China.
Xiaohong HuangDepartment of Stomatology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Yawen ZhangSchool of Basic Medical Sciences, Fujian Medical University, Fuzhou, 350122, China.
Lingyi HuangDepartment of Pediatrics, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China. drhly@fjmu.edu.cn.
Guohao ChenDepartment of Otolaryngology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China. 13705919709@163.com.
Yan JiangDepartment of Stomatology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China. jy2693@fjmu.edu.cn.

Funding

Fujian Provincial Health Technology Project 2025GGA044Natural Science Fundation of Fujian Province 2026J001457Science and Technology Achievement Transformation Fund of The First Affiliated Hospital of Fujian Medical University 2025FY-ZH-09the Joint Funds for the Innovation of Science and Technology of Fujian province 2024Y9154
6 · The paper itself

Abstract

backgroundThis study aimed to evaluate the comprehensive efficacy of van Beek Headgear Activator (VB) in treating adolescent Upper Airway Resistance Syndrome (UARS) patients with mouth breathing-induced high-angle skeletal Class II malocclusion.

methodsPatients were divided into a VB group and a control group. Lateral cephalometric radiographs taken at baseline (T0) and post-treatment (T1) were analyzed for craniofacial changes. Upper airway morphology and function were evaluated using the lateral cephalometric adenoid-to-nasopharyngeal length ratio (A/N), polysomnography results (PSG), and OSA-18 scores. Cone-beam computed tomography was used to assess transverse discrepancies (T-W: maxillary width - mandibular width - 5 mm). And the distribution of height and weight percentiles was compared between the two groups.

resultsA total of 48 subjects were enrolled in this study, with 30 in the VB group and 18 in the control group. In the VB group, SNA (mean decrease: 1.62°) and FH-NA (median decrease: 1.55°) showed significant pre-post reductions, and these changes were significantly different from those in the control group (all p < 0.001). Additionally, mandibular growth was moderately stimulated in the VB group, with Co-Go length showing a statistically significant median increase of 3.70 mm (p < 0.001). VB appliance therapy significantly improved transverse discrepancy, with a mean increase of 4.47 mm in the T-W value (p < 0.001). Over the observation period, both groups showed highly significant improvements in all airway outcomes and quality-of-life outcomes (A/N, AHI, minimum SpO₂, and OSA-18 scores; all p ≤ 0.01), with significantly greater improvements in the VB group across all parameters (all p < 0.001). A significant increase in height and weight percentiles was observed in the VB group (p < 0.001), whereas no changes were observed in the control group.

conclusionsIn a subset of children with conditional UARS who do not meet typical surgical indications, after the use of the VB functional appliance, improvements in sagittal jaw relationship and increases in transverse maxillary width were observed. Compared with the control group, the VB group showed certain improvements in airway-related parameters, sleep respiratory indices, and growth and development metrics, thereby providing preliminary evidence supporting non‑surgical intervention for this condition.

Indexed as

Activator AppliancesExtraoral Traction AppliancesMalocclusion, Angle Class IIMaxillofacial DevelopmentSleep Apnea, ObstructiveAdenoidsAdolescentAirway ResistanceCephalometryChildCone-Beam Computed TomographyFemaleHumansMaleMandibleMaxillaCBCTCephalometricsGrowth and developmentSkeletal Class II malocclusionUpper Airway Resistance Syndromevan Beek Headgear Activator

Identifiers

PMID42365272
PMCPMC13573400

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.