Evidence map›Paper›PMID 42365160›Full record

ArticleAnnals of surgical oncology2026

Risk Factors for Anastomotic Leaks in Simultaneous Resection of Primary Colon Cancer with Synchronous Liver Metastasis: A NSQIP Study.

Allen T Yu, Clark Pitcher, Sergey Khaitov, Parissa Tabrizian, Randolph Steinhagen, Sue J Hahn, James O Park, Noah A Cohen

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Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Allen T YuDepartment of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Clark PitcherDepartment of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sergey KhaitovDepartment of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Parissa TabrizianDepartment of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Randolph SteinhagenDepartment of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sue J HahnDepartment of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
James O ParkDepartment of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Noah A CohenDivision of Hepatobiliary and Pancreatic Surgery Oncology, Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA. Noah.Cohen@NYULangone.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAnastomotic leaks (AL) are a devastating complication of simultaneous resection of primary colon cancer and liver metastases. We aimed to determine the risk factors of AL using a 10-year cohort from a nationwide database. PATIENTS AND

methodsThe American College of Surgeons National Surgical Quality Improvement Program (NSQIP) from 2014 to 2023 was used. Patients who underwent simultaneous colectomy and liver resection were included. Multivariate analysis was performed with AL as the outcome variable. The 2:1 propensity score matching (PSM) was performed on preoperative and operative covariates.

resultsA total of 1517 patients were included. Median age was 60 years and 824 (54%) were male. Most liver resections were minor hepatectomies (87%). In total, 80 (5.3%) patients developed AL. On univariate analysis, higher ASA score, chronic steroid use, and intraoperative blood transfusion were statistically significant risk factors for AL. Multivariate analysis showed that higher ASA score (OR

conclusionsIn this study, we found that a higher ASA score, chronic steroid use, major hepatectomies, and blood transfusions were independent predictors of AL. In matched cohorts, there was also an increased risk for AL. Thus, for high-risk patient populations undergoing simultaneous resection of primary colon cancer and liver metastasis, consideration should be given for fecal diversion or staged procedures.

Indexed as

Anastomotic LeakColectomyColonic NeoplasmsHepatectomyLiver NeoplasmsAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisPropensity ScoreRetrospective StudiesRisk Factors

Identifiers

PMID42365160

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.