ArticleNaunyn-Schmiedeberg's archives of pharmacology2026
Pseudomonas aeruginosa ST4936 with extensive antibacterial drug resistance and virulence determinants from ureteral stent biofilms: whole-genome insights.
Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Newly emerging Pseudomonas aeruginosa sequence types carrying diverse antibacterial resistance and virulence determinants pose serious clinical concerns. This study aimed to characterize the genomic features of P. aeruginosa isolates recovered from ureteral stent biofilms, focusing on antibacterial drug resistance genes, virulence determinants, and mobile genetic elements. P. aeruginosa isolates were confirmed phenotypically and underwent whole-genome sequencing. Multilocus sequence typing and phylogenomic, pangenomic analysis, and comprehensive bioinformatics tools were used to investigate the genomic determinants. All isolates belonged to ST4936 and clustered together phylogenetically, while exhibiting notable genomic variations. Resistome analysis identified acquired resistance genes, including bla
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