Evidence map›Paper›PMID 42364257›Full record

ReviewCurrent opinion in immunology2026

Germinal center responses at barrier organ sites.

William S Foster, Carla R Nowosad

Abstract readReview
In one paragraph

Review in Current opinion in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

William S FosterDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA. Electronic address: william.foster@nyulangone.org.
Carla R NowosadDepartment of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.

Funding

Intestinal Programming of Gut-Associated Germinal CentersR01AI190164 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Carla Rose Nowosad · 2026 to 2026
$792k
NIAID NIH HHS R01 AI190164
6 · The paper itself

Abstract

In this review, we detail the features of barrier germinal centers (GC) that form in tertiary lymphoid structures (TLSs) within non-immune organs that host a local microbiome, and posit a framework of immunity where TLS-GCs created at barrier sites are a key part of normal humoral immunity, and that they form the first layer of an intended multi-layered and increasingly defensive adaptive immune system, providing complementary tissue-specific responses, alongside the local secondary lymphoid organ network and systemic immune responses.

Indexed as

Germinal CenterTertiary Lymphoid StructuresAdaptive ImmunityAnimalsHumansImmunity, HumoralMicrobiota

Identifiers

PMID42364257
PMCPMC13426849

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.