Evidence map›Paper›PMID 42364056›Full record

ReviewScience China. Life sciences2026

Insights from adaptive immune regulation for disease resistance breeding in livestock and poultry.

Peiyao Yan, Kun Yang, Wenhao Xu, Jiarui Zhang, Wanting Zhong, Zhe Wang, Jiahui Zhang, Wenting Li, Kejun Wang, Yaofeng Zhao and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Science China. Life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Peiyao Yan *State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.
Kun Yang *State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.
Wenhao Xu *State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.
Jiarui Zhang *State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.
Wanting ZhongState Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.
Zhe WangState Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.
Jiahui ZhangState Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.
Wenting LiCollege of Animal Science and Technology, Henan Agricultural University, Henan Key Laboratory for Innovation and Utilization of Chicken Germplasm Resources, Zhengzhou, 450046, China.
Kejun WangCollege of Animal Science and Technology, Henan Agricultural University, Henan Key Laboratory for Innovation and Utilization of Chicken Germplasm Resources, Zhengzhou, 450046, China.
Yaofeng ZhaoState Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.
Donghua LiCollege of Animal Science and Technology, Henan Agricultural University, Henan Key Laboratory for Innovation and Utilization of Chicken Germplasm Resources, Zhengzhou, 450046, China. lidonghua6656@126.com.
Shuyang YuState Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China. ysy@cau.edu.cn.
Xiangtao KangCollege of Animal Science and Technology, Henan Agricultural University, Henan Key Laboratory for Innovation and Utilization of Chicken Germplasm Resources, Zhengzhou, 450046, China. kangxiangtao@henau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a crucial component of agriculture, livestock and poultry production supplies high-quality animal protein and is essential for the stability of food safety, ecological environment, human health, and global sustainability. However, frequent epidemics have emerged as a major constraint on industry development, with traditional vaccine and drug-based controls facing challenges such as rapid pathogen mutation, environmental pollution, and drug residue risks. Disease-resistant breeding thus offers a crucial strategy for sustainable livestock farming, yet its progress is hindered by the lack of effective molecular targets for major epizootics. Extensive studies on adaptive immune regulation have identified numerous regulatory genes and molecular targets associated with disease resistance, offering significant potential for breeding applications. Nevertheless, despite the well-established role of adaptive immunity in human medicine, its utilization in livestock breeding remains largely underdeveloped. This review outlines the significance and current status of disease-resistant breeding, focuses on adaptive immune mechanisms, and proposes innovative strategies.

Indexed as

adaptive immunitybreedingdisease resistancegene mininglivestockpoultry

Identifiers

PMID42364056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.