Evidence map›Paper›PMID 42363943›Full record

ReviewMolecular biology reports2026

Natural extracts for the treatment of atherosclerosis.

Ming Li, Zhibo Li, Zhuo Zhao, Ziyuan Guo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ming LiDepartment of Cardiovascular Internal Medicine, the Second Hospital of Jilin University, Changchun, China.
Zhibo LiDepartment of Cardiovascular Internal Medicine, the Second Hospital of Jilin University, Changchun, China.
Zhuo ZhaoDepartment of Cardiovascular Internal Medicine, the Second Hospital of Jilin University, Changchun, China.
Ziyuan GuoDepartment of Cardiovascular Internal Medicine, the Second Hospital of Jilin University, Changchun, China. guoziyuan@jlu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis (AS) is a cardiovascular disease with high mortality and disability rates, and the increasing number of cases urgently demands more effective therapeutic options. AS is characterized by complex pathogenesis and multiple complications, where single-drug therapy has limited efficacy and combination therapy increases safety risks. Natural extracts (NEs) offer advantages such as multi-target, multi-pathway effects and low side effects, showing significant potential in AS prevention and adjunctive treatment. This article systematically reviews existing studies and analyzes the advantages and limitations of NEs in cardiovascular disease management. The development of novel formulations using modern biotechnology and drug delivery systems holds promise for better AS treatment. Although challenges remain in bioavailability and pharmacokinetics, ongoing advances in extraction techniques, delivery systems, and nanotechnology warrant further research into NEs for AS therapy.

Indexed as

AtherosclerosisBiological ProductsPlant ExtractsAnimalsDrug Delivery SystemsHumansBiological ProductsPlant ExtractsAtherosclerosisDrug deliveryMedicineNatural extractPathogenesisTreatment mechanism

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.