Evidence map›Paper›PMID 42363882›Full record

ArticleBiomacromolecules2026

Engineering Coil-Coiled Domains for the Design of Modular Theranostic Agents: Galectin-3 as a Targeting Moiety.

Chiara Burgio, Maria D Giron, Mariano Ortega-Muñoz, Daniel Lucena, Rafael Salto

Abstract read
In one paragraph

Article in Biomacromolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chiara BurgioDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, Granada E-18071, Spain.ORCID 0009-0005-6450-4667
Maria D GironDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, Granada E-18071, Spain.ORCID 0000-0001-9638-988X
Mariano Ortega-MuñozDepartment of Organic Chemistry, School of Sciences, Biotechnology Institute, University of Granada, Granada, E-18071 Spain.
Daniel LucenaDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, Granada E-18071, Spain.ORCID 0009-0005-1219-7087
Rafael SaltoDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, Granada E-18071, Spain.ORCID 0000-0002-7044-3611

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To generate drug-targeting agents with a modular and efficient design for disease treatments, including cancer, we used protein coil-coiled dimerization motifs to eliminate the need for chemical conjugation techniques, generating a versatile theranostic system: a targeting moiety genetically fused to an E

Indexed as

Drug Delivery SystemsGalectin 3Protein EngineeringTheranostic NanomedicineAnimalsBlood ProteinsCell Line, TumorDoxorubicinGalactosidesGalectinsHumansMaltose-Binding ProteinsMiceRecombinant Fusion ProteinsStreptavidinbeta-galactosideBlood ProteinsDoxorubicinGalactosidesGalectin 3GalectinsLGALS3 protein, humanMaltose-Binding ProteinsRecombinant Fusion ProteinsStreptavidin

Identifiers

PMID42363882
PMCPMC13370767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.