Evidence map›Paper›PMID 42363838›Full record

ArticleClinical cardiology2026

Inpatient Outcomes and Complications After Left Atrial Appendage Occlusion in Rural Versus Urban Hospitals in the United States.

Amanda Nguyen, Muhammad Zia Khan, Joseph Neely, Waleed Alruwaili, Muhammad Abdullah Naveed, Justin Lim Devera, William E Leon, Siddharth Agarwal, Zain Ul Abideen Asad, Samrina Khan and 3 more

Abstract readMulticenter StudyComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Amanda NguyenDepartment of Medicine, University of California Davis Medical Center, Sacramento, California, USA.
Muhammad Zia KhanDivision of Cardiology, Deborah Heart and Lung Center, Browns Mills, New Jersey, USA.
Joseph NeelyDepartment of Medicine, University of California Davis Medical Center, Sacramento, California, USA.
Waleed AlruwailiDepartment of Medicine, West Virginia University, Morgantown, West Virginia, USA.
Muhammad Abdullah NaveedDepartment of Cardiology, Dow Medical College, Karachi, Pakistan.ORCID https://orcid.org/0009-0006-9230-6569
Justin Lim DeveraSection of Electrophysiology, Division of Cardiology, University of California Davis, Sacramento, California, USA.
William E LeonSection of Electrophysiology, Division of Cardiology, University of California Davis, Sacramento, California, USA.
Siddharth AgarwalDepartment of Cardiology, Mayo Clinic, Rochester, Minnesota, USA.
Zain Ul Abideen AsadDivision of Cardiology, University of Oklahoma, Oklahoma City, Oklahoma, USA.
Samrina KhanDepartment of Medicine, Khyber Medical University, Peshawar, Pakistan.
Karthik GonuguntlaDivision of Cardiology, Hartford Hospital Heart and Vascular Institute, Norwich, Connecticut, USA.ORCID https://orcid.org/0000-0002-5607-7993
Daniel IceDivision of Cardiology, Deborah Heart and Lung Center, Browns Mills, New Jersey, USA.
Muhammad Bilal MunirSection of Electrophysiology, Division of Cardiology, University of California Davis, Sacramento, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDisparities in management of atrial fibrillation in rural and urban hospitals across the U.S. have been reported. However, studies investigating disparities regarding outcomes and complications after left atrial appendage occlusion (LAAO) based on hospital location are lacking.

objectiveTo evaluate differences in outcomes and complications related to LAAO among rural and urban hospitals.

methodsThe National Inpatient Sample was used to identify patients who underwent LAAO implantations in the U.S. from 2016-2020. Study endpoints assessed included inpatient complications, outcomes, and resource utilization after LAAO procedures among rural and urban hospitals.

resultsFrom 2016-2020, there were a total of 87 315 and 1985 LAAO device placements in urban and rural hospitals, respectively. Baseline characteristics were similar among both groups, with a few exceptions. After multivariable adjustment for confounders, odds of inpatient complications and mortality were similar among both groups. However, rural LAAO recipients experienced greater rates of discharge to an acute care facility (3.3% vs 2.4%, p = 0.01), as well as lower costs (aOR: 0.58, 95% CI: 0.49-0.69) and length of stay (aOR: 0.89, 95% CI: 0.81-0.98).

conclusionsA majority of LAAO implantations occurred in urban hospitals in the U.S. Baseline characteristics and adjusted odds of inpatient complications and mortality were similar in rural and urban recipients. However, important differences were described regarding resource utilization and disposition. Further investigation into the specific factors driving these inequities is encouraged to promote improved access to and outcomes of cardiovascular care for rural residents.

Indexed as

Atrial AppendageAtrial FibrillationHospitals, RuralHospitals, UrbanInpatientsLeft Atrial Appendage ClosurePostoperative ComplicationsAgedFemaleFollow-Up StudiesHumansMaleRetrospective StudiesRisk FactorsTreatment OutcomeUnited Statesdisparitiesleft atrial appendage occlusionoutcomesruralurban

Identifiers

PMID42363838
PMCPMC13309940

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.