Trial reportJournal of gastroenterology and hepatology2026
The Addition of Computer-Aided Detection (CADe) to Texture and Color Enhancement Imaging (TXI) Does Not Improve Adenoma Detection Rate During Colonoscopy: A Prospective Study.
Trial report in Journal of gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Comment on: The Addition of Computer-Aided Detection (CADe) to Texture and Color Enhancement Imaging (TXI) Does Not Improve Adenoma Detection Rate During Colonoscopy: A Prospective Study.Journal of gastroenterology and hepatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesEarly detection and resection of colorectal polyps prevent their progression toward advanced adenocarcinomas. The use of Texture and Color Enhancement Imaging (TXI) has been demonstrated to enhance adenoma detection compared to white light imaging. It remains unknown whether there is an additive benefit when using computer-aided detection (CADe) in addition to enhanced imaging technologies.
methodsThis prospective study involved the combined use of TXI and CADe during colonoscope withdrawal in the intervention group, compared against historical controls from a prior randomized controlled trial using TXI alone. The presence and number of colonic polyps identified, resected, and analyzed via histopathology were documented and compared between groups.
resultsA total of 263 patients were included in the analysis, 100 in the TXI and CADe group and 163 in the TXI-only group. There was no difference in the number of adenomas per colonoscopy (mean 1.71 in both groups, p > 0.99) or the adenoma detection rate (ADR) (62% with TXI and CADe vs. 55.8% with TXI alone, p = 0.33). In standard-detector endoscopists, there was an improvement in ADR using TXI and CADe compared with TXI alone (63% vs. 44%, p = 0.046). There was an almost 1-min increase in mean withdrawal time with TXI and CADe (p < 0.001) and an increase in the resection of non-neoplastic polyps (27% vs. 16.6%, p = 0.042).
conclusionsThe addition of CADe did not impact overall adenoma detection, although it did improve adenoma detection in those with an ADR < 55%. This comes at the cost of increased withdrawal time and more frequent resection of non-neoplastic polyps.
trial registrationAustralian New Zealand Clinical Trials Registry: ACTRN12625000996460.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.