Evidence map›Paper›PMID 42363183›Full record

ArticleBMC veterinary research2026

Unique occurrence of trichilemmal carcinoma in the scrotal skin of a giant panda: a pathological analysis.

Chengyao Li, Zongliang Xiong, Shanshan Ling, Yan Zhu, Linhua Deng, Mengfang Yang, Chengdong Wang, Qian Wang, Danyu Chen, Mao Huang and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Chengyao Li *Key Laboratory of SFGA on the Giant panda, China Conservation and Research Center for the Giant Panda, Chengdu, China.
Zongliang Xiong *Experimental Animal Disease Model Research Laboratory, School of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Shanshan Ling *Key Laboratory of SFGA on the Giant panda, China Conservation and Research Center for the Giant Panda, Chengdu, China.
Yan ZhuKey Laboratory of SFGA on the Giant panda, China Conservation and Research Center for the Giant Panda, Chengdu, China.
Linhua DengKey Laboratory of SFGA on the Giant panda, China Conservation and Research Center for the Giant Panda, Chengdu, China.
Mengfang YangKey Laboratory of SFGA on the Giant panda, China Conservation and Research Center for the Giant Panda, Chengdu, China.
Chengdong WangKey Laboratory of SFGA on the Giant panda, China Conservation and Research Center for the Giant Panda, Chengdu, China.
Qian WangKey Laboratory of SFGA on the Giant panda, China Conservation and Research Center for the Giant Panda, Chengdu, China.
Danyu ChenKey Laboratory of SFGA on the Giant panda, China Conservation and Research Center for the Giant Panda, Chengdu, China.
Mao HuangDujiangyan People's Hospital, Chengdu, China.
Kao WangDujiangyan People's Hospital, Chengdu, China.
Desheng LiKey Laboratory of SFGA on the Giant panda, China Conservation and Research Center for the Giant Panda, Chengdu, China.
Zhengli ChenExperimental Animal Disease Model Research Laboratory, School of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China. chzhli75@163.com.
Caiwu LiKey Laboratory of SFGA on the Giant panda, China Conservation and Research Center for the Giant Panda, Chengdu, China. licaiwu118@163.com.

Funding

The key project of the National Forestry and Grassland Administration of China CGF2024001
6 · The paper itself

Abstract

backgroundTrichilemmal carcinoma (TC) is a rare cutaneous appendage malignancy with scarce human cases and very few animal cases have been documented in the available literature, especially in giant pandas. CASE PRESENTATION: A 23-year-old male captive giant panda had 4-week scrotal hyperplasia and ulceration, with a 4.5 cm×4 cm irregular lesion and neutrophils were elevated. Pathology revealed dermal lobular/cord-like invasive atypical clear cells, squamous nests and outer root sheath cysts. PAS staining was positive. Immunohistochemistry showed Her-2 (+), CK5/6 (++), p63 (++), Ki-67 (+), CD34 (+), and p53 (+), excluding squamous cell carcinoma and trichofolliculoma. Local resection (0.8 cm margin) was done under general anesthesia. Postoperative anti-infection led to 2-week wound healing; 3-month follow-up showed no recurrence with normal behavior.

conclusionsThis first reported giant panda TC with human-like immunophenotype provides evidence for managing rare animal cutaneous appendage tumors.

Indexed as

Carcinoma, Skin AppendageScrotumSkin NeoplasmsUrsidaeAnimalsMaleGiant panda (Ailuropoda melanoleuca)HistopathologyImmunohistochemistrySurgical treatmentTrichilemmal carcinoma

Identifiers

PMID42363183
PMCPMC13573345

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