Evidence map›Paper›PMID 42363050›Full record

ArticleBMC genomics2026

Genomic distribution characteristics and interspecific differences of microsatellite landscapes in Felidae.

Hailong Dou, Hongyuan Xi, Yujian Li, Haitao Yang, Honghai Zhang, Fang Wang

Abstract read
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Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hailong Dou *School of Life Sciences, Fudan University, Shanghai, 200438, China. hellohailong@163.com.
Hongyuan Xi *College of Life Science, Qufu Normal University, Qufu, 273165, China.
Yujian LiCollege of Life Science, Qufu Normal University, Qufu, 273165, China.
Haitao YangSchool of Ecology, Hainan University, Haikou, 570228, China.
Honghai ZhangCollege of Life Science, Qufu Normal University, Qufu, 273165, China.
Fang WangSchool of Life Sciences, Fudan University, Shanghai, 200438, China. wfang@fudan.edu.cn.

Funding

National Natural Science Foundation of China 31800452
6 · The paper itself

Abstract

backgroundMicrosatellites within genomes play crucial roles in regulating gene expression, DNA replication, and chromosomal structure and function. Analyzing the composition and distribution patterns of microsatellites in closely related species not only reveals their evolutionary dynamics and adaptive mechanisms but also provides essential technical support for applications in genetic breeding, species conservation, and disease research. As one of the world's most captivating animal groups, the landscape patterns of microsatellites across feline genomes remain to be systematically characterized.

resultsThis study utilized high-quality genomic data to conduct a systematic comparative analysis of microsatellite landscape distribution patterns across the genomes of 13 felid species. The findings revealed that microsatellite abundance and distribution exhibit species-specific characteristics, with a non-random genomic distribution and a negative correlation between microsatellite abundance and repeat length. The predominant distribution pattern followed the sequence: single > double > quadruple > triple > quintuple > sextuple nucleotide repeats. Microsatellite abundance peaked in intergenic regions, whereas trinucleotide repeats were more prevalent within exons. Coding regions showed a marked preference for trinucleotide and hexanucleotide repeats. Enrichment analysis of GO and KEGG pathways indicated that coding sequences containing microsatellites were primarily involved in transcription and translation processes.

conclusionsOur study elucidates the distribution patterns and characteristics of microsatellites across diverse feline species, providing significant insights into their evolutionary mechanisms and functional roles. Furthermore, these findings establish a valuable reference and foundational dataset for the future development of high-quality, species-specific microsatellite markers in felids.

Indexed as

FelidaeGenomeGenomicsMicrosatellite RepeatsAnimalsSpecies SpecificityDistribution patternsFelidsFunctional annotationGenomeMicrosatellites

Identifiers

PMID42363050
PMCPMC13563790

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