Evidence map›Paper›PMID 42362954›Full record

ArticleCommunications biology2026

Genome evolution and transposable element expansion reveal host-associated genomic features in Cladosporium cucumerinum.

Xuanjun Lu, Qianxi Li, Yulan Zeng, Zhenfeng Bai, Mengrong Wang, Wenxiu Zheng, Hongkai Wang, Jiandong Bao, Xihui Xu, Xuetao Shi and 2 more

Abstract read
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In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xuanjun LuState Key Laboratory for Quality and Safety of Agro-products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Biotechnology, Zhejiang University, Hangzhou, China.
Qianxi LiState Key Laboratory for Quality and Safety of Agro-products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Biotechnology, Zhejiang University, Hangzhou, China.
Yulan ZengState Key Laboratory for Quality and Safety of Agro-products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Key Laboratory of Agricultural Microbiome (MARA), Institute of Plant Protection and Microbiology, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.
Zhenfeng BaiState Key Laboratory for Quality and Safety of Agro-products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Biotechnology, Zhejiang University, Hangzhou, China.
Mengrong WangState Key Laboratory for Quality and Safety of Agro-products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Biotechnology, Zhejiang University, Hangzhou, China.
Wenxiu ZhengState Key Laboratory for Quality and Safety of Agro-products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Biotechnology, Zhejiang University, Hangzhou, China.
Hongkai WangState Key Laboratory for Quality and Safety of Agro-products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Biotechnology, Zhejiang University, Hangzhou, China.
Jiandong BaoState Key Laboratory for Quality and Safety of Agro-products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Key Laboratory of Agricultural Microbiome (MARA), Institute of Plant Protection and Microbiology, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.ORCID http://orcid.org/0000-0003-3423-5118
Xihui XuCollege of Life Sciences, Nanjing Agricultural University, Nanjing, China.ORCID http://orcid.org/0000-0003-2092-9987
Xuetao ShiXianghu Laboratory, Hangzhou, China.
Zhenzhu SuState Key Laboratory for Quality and Safety of Agro-products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Biotechnology, Zhejiang University, Hangzhou, China.
Fucheng LinState Key Laboratory for Quality and Safety of Agro-products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Biotechnology, Zhejiang University, Hangzhou, China. fuchenglin@zju.edu.cn.ORCID http://orcid.org/0000-0002-4127-8143

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

How pathogens adapt to specific hosts remains an open question. Here, we investigate Cladosporium cucumerinum, a pathogen largely associated with Cucurbitaceae. Comparative genomic analysis of five newly Cladosporium sequenced genomes together with 19 publicly available genomes indicates that the diversification of C. cucumerinum occurred after that of its cucumber host lineage. We observe gene family contraction alongside lineage-specific expansion of long terminal repeat retrotransposons, accompanied by variation in gene repertoires including carbohydrate-active enzymes and secondary metabolite gene clusters. A lineage-specific β-glucosidase, CcBGL258, is required for pathogenicity but is dispensable for vegetative growth under in vitro conditions. Transcriptomic analyses reveal dynamic changes in gene expression during infection in both the pathogen and the host. Together, these results provide a genomic framework for host-associated features in C. cucumerinum, although we highlight that several associations observed in the study remain correlative and require further functional validation.

Indexed as

CladosporiumDNA Transposable ElementsEvolution, MolecularGenome, FungalHost-Pathogen InteractionsPlant DiseasesCucumis sativusGenomicsPhylogenyDNA Transposable Elements

Identifiers

PMID42362954

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.