Evidence map›Paper›PMID 42362891›Full record

ArticleApplied microbiology and biotechnology2026

Poly(3-hydroxybutyrate) production from ricotta whey by Cupriavidus necator: effects of coffee oil and oxidative stress.

Angela Longo, Andrea Torreggiani, Luca Sconosciuto, Michela Verni, Vito Emanuele Carofiglio, Domenico Centrone, Marianna Villano, Gaia Salvatori, Erica Pontonio, Marco Montemurro and 1 more

Abstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Angela LongoDepartment of Environmental Biology, Sapienza University of Rome, 00185, Rome, Italy.
Andrea TorreggianiDepartment of Soil, Plant and Food Science, University of Bari, 70126, Bari, Italy.
Luca SconosciutoEggPlant Srl, 00198, Rome, Italy.
Michela VerniDepartment of Environmental Biology, Sapienza University of Rome, 00185, Rome, Italy.
Vito Emanuele CarofiglioEggPlant Srl, 00198, Rome, Italy.
Domenico CentroneEggPlant Srl, 00198, Rome, Italy.
Marianna VillanoDepartment of Chemistry, Sapienza University of Rome, 00185, Rome, Italy.
Gaia SalvatoriDepartment of Chemistry, Sapienza University of Rome, 00185, Rome, Italy.
Erica PontonioDepartment of Soil, Plant and Food Science, University of Bari, 70126, Bari, Italy.
Marco MontemurroInstitute of Sciences of Food Production, (CNR-ISPA), National Research Council of Italy, 70126, Bari, Italy.
Carlo G RizzelloDepartment of Environmental Biology, Sapienza University of Rome, 00185, Rome, Italy. carlogiuseppe.rizzello@uniroma1.it.ORCID https://orcid.org/0000-0002-0425-2892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, ricotta cheese exhausted whey (RCEW), an abundant dairy by-product, was evaluated as a low-cost substrate for poly(3-hydroxybutyrate) (PHB) production by Cupriavidus necator DSM 428 through an integrated process strategy combining substrate conditioning, enzymatic lactose hydrolysis, oxidative stress modulation, and cultivation under controlled bioreactor conditions. Shake-flask experiments demonstrated that RCEW supported efficient biomass formation (1.60 g L⁻

Indexed as

CoffeeCupriavidus necatorHydroxybutyratesOxidative StressPlant OilsPolyestersWheyBiomassBioreactorsCheeseFermentationHydrogen PeroxidePolyhydroxybutyratesCoffeeHydrogen PeroxideHydroxybutyratesPlant Oilspoly-beta-hydroxybutyratePolyestersPolyhydroxybutyratesCupriavidus necatorFed-batch fermentationOxidative stressPHBWhey

Identifiers

PMID42362891
PMCPMC13554019

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.