Evidence map›Paper›PMID 42362783›Full record

ArticleJournal of neurology2026

A model of see-saw nystagmus.

Marcello Cherchi

Abstract read
In one paragraph

Article in Journal of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Marcello CherchiDepartment of Neurology, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL, 60637, USA. marcello.cherchi@bsd.uchicago.edu.ORCID http://orcid.org/0000-0002-9371-4488

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

See-saw nystagmus (SSN), and the possibly related hemi-see-saw nystagmus (hSSN), occur in certain forms of visual loss and in some brainstem lesions. These disparate lesions have made it challenging for investigators to arrive at a unified mechanism. Here we propose a model involving detection of peripheral retinal disparity in the superior colliculi (SC), which send inhibitory projections to the interstitial nucleus of Cajal (INC) that maintain calibration, and how loss of such calibration may provoke INC neurons (which are already mutually inhibitory with contralateral INC neurons) to develop self-inhibitory axo-dendritic autapses, resulting in a network configuration from which a pathologic Matsuoka oscillator can emerge and drive the alternating vertical and torsional movements characteristic of SSN and hSSN.

Indexed as

Models, NeurologicalNystagmus, PathologicSuperior ColliculiAnimalsHumansVisual PathwaysControl systems analysisInterstitial nucleus of CajalModelingNystagmusSee-saw nystagmusSuperior colliculus

Identifiers

PMID42362783
PMCPMC13309414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.