Evidence map›Paper›PMID 42362582›Full record

Articlenpj aging2026

Association between socioeconomic position and transitions to multimorbidity involving major chronic diseases in Northwest Italy.

Francesca Mori, Luca Manfredi, Roberto Gnavi, Elisa Ferracin, Roberta Picariello, Lorenzo Milani, Federica Buscema, Maria Teresa Giraudo, Fulvio Ricceri

Abstract read
In one paragraph

Article in npj aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesca Mori *Department of Mathematics, University of Turin, Turin, Italy.
Luca Manfredi *Department of Clinical and Biological Sciences, Centre for Biostatistics, Epidemiology, and Public Health, University of Turin, Turin, Italy.
Roberto GnaviEpidemiology Unit ASL TO3, Collegno, Italy.
Elisa FerracinEpidemiology Unit ASL TO3, Collegno, Italy.
Roberta PicarielloEpidemiology Unit ASL TO3, Collegno, Italy.
Lorenzo MilaniDepartment of Clinical and Biological Sciences, Centre for Biostatistics, Epidemiology, and Public Health, University of Turin, Turin, Italy.
Federica BuscemaDepartment of Clinical and Biological Sciences, Centre for Biostatistics, Epidemiology, and Public Health, University of Turin, Turin, Italy.
Maria Teresa GiraudoDepartment of Clinical and Biological Sciences, Centre for Biostatistics, Epidemiology, and Public Health, University of Turin, Turin, Italy. mariateresa.giraudo@unito.it.
Fulvio RicceriDepartment of Clinical and Biological Sciences, Centre for Biostatistics, Epidemiology, and Public Health, University of Turin, Turin, Italy.

Funding

Ministero della Salute PNRR-MAD-2022-12376416
6 · The paper itself

Abstract

Multimorbidity, the co-occurrence of multiple chronic conditions in individuals, complicates clinical management, increases healthcare use, and reduces life quality. This study investigates the association between socioeconomic position and multimorbidity, restricted to co-occurrence of two or more conditions among type 2 diabetes, cardiovascular diseases, selected cancers as a single category, chronic obstructive pulmonary disease, and depression, in a population-based cohort in Piedmont, Italy. A multimorbidity registry was built from 2013 to 2019, and diseases were identified through healthcare databases. Multistate models estimated the association between multimorbidity and socioeconomic position, stratifying by sex. Among 1,534,975 individuals, multimorbidity incidence was 1.31 (95% CI: 1.29-1.33) per 100,000 person-days. Lower SEP was associated with higher risk in almost all transitions to T2D and to CVD. In women, borderline significant associations were found from cancer to depression and from COPD to depression, comparing the lowest to the highest SEP. In men, significant associations were found for transitions to COPD as well as from COPD to cancer and from depression to cancer. Lower SEP was consistently associated with higher risks of single diseases and multimorbidity, with some sex-specific patterns. These findings highlight cumulative disadvantage and the need for policies targeting health inequalities in aging populations.

Identifiers

PMID42362582
PMCPMC13669304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.