Evidence map›Paper›PMID 42362353›Full record

ArticleRNA (New York, N.Y.)2026

Optimized tRNA structure-seq reveals robust tRNA secondary structures in

Komei Yanagihara, Futa Konishi, Teppei Matsuda, Akira Hirata, Hiroyuki Hori, Philip C Bevilacqua, Ryota Yamagami

Abstract read
PubMed Publisher
In one paragraph

Article in RNA (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A passive protein environment offsets RNA folding energetics in cells.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Komei YanagiharaDepartment of Applied Chemistry, Graduate School of Science and Engineering, Ehime University, Ehime 790-8577, Japan.
Futa KonishiDepartment of Applied Chemistry, Graduate School of Science and Engineering, Ehime University, Ehime 790-8577, Japan.
Teppei MatsudaDepartment of Applied Chemistry, Graduate School of Science and Engineering, Ehime University, Ehime 790-8577, Japan.
Akira HirataDepartment of Natural Science, Division of Science and Technology, Graduate School of Sciences and Technology for Innovation, Tokushima University, Tokushima 770-8506, Japan.
Hiroyuki HoriDepartment of Applied Chemistry, Graduate School of Science and Engineering, Ehime University, Ehime 790-8577, Japan.
Philip C BevilacquaDepartment of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID http://orcid.org/0000-0001-8074-3434
Ryota YamagamiDepartment of Applied Chemistry, Graduate School of Science and Engineering, Ehime University, Ehime 790-8577, Japan yamagami.ryota.bn@ehime-u.ac.jp.ORCID http://orcid.org/0000-0002-6947-1906

Funding

RNA folding and catalysis at the interface of biophysics and genomicsR35GM127064 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI PHILIP C BEVILACQUA · 2018 to 2026
$3.4M
NIGMS NIH HHS R35 GM127064
6 · The paper itself

Abstract

RNA structure plays a crucial role in diverse biological processes beyond the translation of genetic information. Therefore, the development of reliable methods for RNA structure prediction is essential for understanding RNA structure-related functions. However, accurate and comprehensive RNA structure prediction remains challenging. Here, we focus on secondary structure prediction of transfer RNA (tRNA) using structure probing coupled with next-generation sequencing (tRNA structure-seq). In silico prediction of

Indexed as

Nucleic Acid ConformationRNA, FungalRNA, TransferSaccharomyces cerevisiaeStress, PhysiologicalBase SequenceHigh-Throughput Nucleotide SequencingSequence Analysis, RNASulfuric Acid Estersdimethyl sulfateRNA, FungalRNA, TransferSulfuric Acid Estersmutation profilingprediction of RNA structurestresstRNAtRNA modificationtRNA structure

Identifiers

PMID42362353

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.