Evidence map›Paper›PMID 42361312›Full record

Trial reportAge and ageing2026

Effects of a home-based exercise and physical activity intervention after inpatient rehabilitation on real-world mobility in older adults with cognitive impairment: a secondary analysis of a randomised controlled trial.

Christian Werner, Phoebe Ullrich, Letizia Degli Angeli, Rieke Trumpf, Tim Fleiner, Jose L Albites-Sanabria, Luca Palmerini, Bastian Abel, Martin Bongartz, Tobias Eckert and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Age and ageing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Christian WernerGeriatric Centre, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Baden-Württemberg, Germany.ORCID 0000-0003-0679-3227
Phoebe UllrichGeriatric Centre, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Baden-Württemberg, Germany.ORCID 0000-0003-2138-1327
Letizia Degli AngeliDepartment of Electrical, Electronic, and Information Engineering "Guglielmo Marconi" - DEI, University of Bologna, Bologna, Italy.
Rieke TrumpfDepartment of Geriatric Psychiatry and Psychotherapy, LVR Hospital Cologne, Cologne, North Rhine-Westphalia, Germany.ORCID 0000-0002-7091-4583
Tim FleinerInstitute for Geriatric Research, Ulm University Medical Centre, Ulm, Baden-Württemberg, Germany.ORCID 0000-0003-2949-940X
Jose L Albites-SanabriaDepartment of Electrical, Electronic, and Information Engineering "Guglielmo Marconi" - DEI, University of Bologna, Bologna, Italy.ORCID 0000-0001-7688-6221
Luca PalmeriniDepartment of Electrical, Electronic, and Information Engineering "Guglielmo Marconi" - DEI, University of Bologna, Bologna, Italy.ORCID 0000-0003-4758-662X
Bastian AbelGeriatric Centre, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Baden-Württemberg, Germany.ORCID 0000-0002-6696-5230
Martin BongartzGeriatric Centre, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Baden-Württemberg, Germany.ORCID 0000-0001-5647-7148
Tobias EckertGeriatric Centre, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Baden-Württemberg, Germany.ORCID 0000-0002-0565-7998
Jürgen M BauerGeriatric Centre, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Baden-Württemberg, Germany.
Klaus HauerGeriatric Centre, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Baden-Württemberg, Germany.ORCID 0000-0001-8041-5705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPersistent mobility limitations after inpatient rehabilitation are common in older adults with cognitive impairment (CI). Home-based exercise interventions can improve locomotor capacity during this vulnerable period; however, evidence that they improve real-world mobility is scarce.

objectiveTo investigate the effects of a home-based exercise programme combined with physical activity (PA) promotion on real-world digital mobility outcomes (DMOs).

designSingle-centre, double-blind, randomised, placebo-controlled trial.

settingCommunity.

participants104 community-dwelling older adults with CI (82.3 ± 6.0 years; 75% women; Mini-Mental State Examination score 23.2 ± 2.4) recently discharged from inpatient geriatric rehabilitation.

methodsThe intervention group received a 12-week home-based exercise programme combined with behavioural change techniques to promote PA; the control group received a 12-week non-specific home-based placebo motor activity programme. DMOs related to walking amount, pattern and pace were measured over 48 h at baseline, post-intervention and after a 12-week follow-up using a single body-fixed sensor and validated processing algorithms.

resultsPost-intervention, small statistically significant improvements favouring the intervention group were observed in walking pattern and pace outcomes, including longer walking bout (WB) duration, higher walking speed and longer stride length in shorter (10-30 s) WBs, and higher 90th percentile walking speed in WBs >10 s. These improvements were not sustained at the 12-week follow-up. No between-group differences were found for walking amount.

conclusionThe post-discharge home-based exercise programme combined with PA promotion showed small, short-term improvements in selected real-world walking pattern and pace outcomes in older adults with CI after inpatient rehabilitation; however, these effects were no longer evident at follow-up, and walking amount did not increase.

Indexed as

Cognitive DysfunctionExerciseExercise TherapyHome Care ServicesInpatientsMobility LimitationAgedAged, 80 and overDouble-Blind MethodFemaleHumansMaleTime FactorsTreatment OutcomeWalkingageingcognitive dysfunctionmotor activityolder peoplewalkingwearable electronic device

Identifiers

PMID42361312
PMCPMC13308959

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.