Observational studyEuropean stroke journal2026
Procedure time and 90-day outcomes after endovascular thrombectomy for large-core stroke.
Observational study in European stroke journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
introductionProcedure time during endovascular thrombectomy (EVT) has been associated with outcomes in general thrombectomy cohorts, but whether this relationship reflects a threshold or continuous risk accumulation in large-core stroke remains unclear. PATIENTS AND
methodsWe performed a retrospective observational analysis of 490 patients with anterior-circulation large-vessel occlusion (LVO) and large-core infarction, defined by an Alberta Stroke Program Early Computed Tomography Score of 5 or less, from a prospective multicentre registry across 38 centres. Procedure time was analysed categorically and continuously. The primary outcome was the 90-day mRS score of 0-3. Secondary outcomes were 90-day mortality and sICH. Restricted cubic splines tested nonlinearity.
resultsEach 10-min increase in procedure time was associated with lower odds of an modified Rankin Scale (mRS) score of 0-3 (odds ratio, 0.91; 95% CI, 0.86-0.95) and higher mortality (odds ratio, 1.07; 95% CI, 1.02-1.11). On the absolute scale, the marginally standardised probability of mRS 0-3 decreased from 44.5% at 60 min to 27.5% at 150 min (absolute risk difference - 17.1 percentage points; 95% CI, - 27.7 to -6.4). Spline analyses showed no evidence of nonlinearity for functional outcome or mortality. No consistent association with sICH was observed across analyses. DISCUSSION: Longer procedure time was associated with progressively worse functional outcome and higher mortality in large-core EVT, without evidence of a clear nonlinear inflection point.
conclusionThese findings support procedure time as a continuous intraprocedural risk indicator that may inform ongoing procedural reassessment. CLINICAL
trial registrationMAGIC registry, ChiCTR.org.cn Identifier: ChiCTR2100051664.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.