Evidence map›Paper›PMID 42361194›Full record

ArticlePLOS global public health2026

Isolation of non-albicans Candida and associated factors among symptomatic women presenting with abnormal vaginal discharge at Mubende Regional Referral Hospital, Central Uganda: A cross-sectional study.

Suleiman Ameir Idrissa, Marie Pascaline Sabine Ishimwe, Musa Kasujja, Maxwell Okello, Theodore Nteziyaremye, Sara Liban, Ahmed Kiswezi Kazigo, Olabisi Surat Akib, Theoneste Hakizimana

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Article in PLOS global public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Suleiman Ameir IdrissaDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, Uganda.ORCID https://orcid.org/0009-0001-7324-3359
Marie Pascaline Sabine IshimweDepartment of Pediatrics and Child Health, Kampala International University, Ishaka, Uganda.
Musa KasujjaDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, Uganda.ORCID https://orcid.org/0009-0000-1861-8181
Maxwell OkelloDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, Uganda.
Theodore NteziyaremyeDepartment of Sciences, University of Rwanda, Kigali, Rwanda.
Sara LibanDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, Uganda.
Ahmed Kiswezi KazigoDepartment of Surgery, Kampala International University, Ishaka, Uganda.
Olabisi Surat AkibDepartment of Pathology, Kampala International University, Ishaka, Uganda.
Theoneste HakizimanaDepartment of Obstetrics and Gynecology, Kampala International University, Ishaka, Uganda.ORCID https://orcid.org/0000-0002-9282-5733

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vulvovaginal infections contribute substantially to women's reproductive morbidity, yet little is known about the determinants of non-albicans Candida (NAC) in sub-Saharan Africa. Understanding population-level drivers is critical for prevention and control. We conducted a hospital-based analytic cross-sectional study among 314 symptomatic women aged 18-49 years presenting with abnormal vaginal discharge at the gynecologic clinic of Mubende Regional Referral Hospital, Central Uganda, between 1st May 2025 and 1st August 2025. High vaginal swabs were cultured and species identified using CHROM agar. Sociodemographic, behavioral, and clinical data were collected through structured interviews. Logistic regression identified determinants of NAC infection. The prevalence of NAC infection was 23.6% (74/314; 95% CI: 19.0-28.8). The most frequently isolated species were C. glabrata (41.9%) and C. tropicalis (29.7%). Key determinants included: having ≥2 sexual partners (aOR 9.41, 95% CI: 4.59-19.31), ≥ 3 vaginal infections in the past year (aOR 6.43, 95% CI: 3.21-12.89), HIV-positive status (aOR 5.37, 95% CI: 2.51-11.49), contraceptive use (aOR 2.70, 95% CI: 1.39-5.24), vaginal douching (aOR 2.25, 95% CI: 1.15-4.41), and recent antibiotic use (aOR 2.09, 95% CI: 1.06-4.11). NAC infections are highly prevalent among women with abnormal vaginal discharge in Uganda, driven by modifiable behavioral and clinical factors. Public health interventions should prioritize sexual health education, discourage vaginal douching, promote rational antibiotic use, and integrate screening and counselling for high-risk women, especially those with HIV. Interpretation should be cautious because alternative etiologies of vaginal discharge were not excluded and confirmatory species identification was not performed.

Identifiers

PMID42361194
PMCPMC13309014

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