Evidence map›Paper›PMID 42361183›Full record

ArticleScience advances2026

Decarboxylative carbonyl alkylative amination: A general and practical strategy for aliphatic amine synthesis.

Ling-Zhi Meng, Yu-Tong Wang, Xiao-Dan Zhang, Hai-Yue Zhou, Di-Di Chen, Hao-Yu Chen, Ying-Zhuang Xu, Wei Su, Tian-Jun Gong

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In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ling-Zhi MengSchool of Science, Hebei Provincial Key Laboratory of Photoelectric Control on Surface and Interface, Hebei University of Science and Technology, Shijiazhuang 050022, China.ORCID 0009-0007-7497-910X
Yu-Tong WangSchool of Science, Hebei Provincial Key Laboratory of Photoelectric Control on Surface and Interface, Hebei University of Science and Technology, Shijiazhuang 050022, China.
Xiao-Dan ZhangSchool of Science, Hebei Provincial Key Laboratory of Photoelectric Control on Surface and Interface, Hebei University of Science and Technology, Shijiazhuang 050022, China.
Hai-Yue ZhouSchool of Science, Hebei Provincial Key Laboratory of Photoelectric Control on Surface and Interface, Hebei University of Science and Technology, Shijiazhuang 050022, China.
Di-Di ChenSchool of Science, Hebei Provincial Key Laboratory of Photoelectric Control on Surface and Interface, Hebei University of Science and Technology, Shijiazhuang 050022, China.
Hao-Yu ChenAnhui Province Key Laboratory of Biomass Chemistry, CAS Key Laboratory of Urban Pollutant Conversion, University of Science and Technology of China, Hefei 230026, China.
Ying-Zhuang XuSchool of Science, Hebei Provincial Key Laboratory of Photoelectric Control on Surface and Interface, Hebei University of Science and Technology, Shijiazhuang 050022, China.ORCID 0009-0007-3141-167X
Wei SuSchool of Science, Hebei Provincial Key Laboratory of Photoelectric Control on Surface and Interface, Hebei University of Science and Technology, Shijiazhuang 050022, China.ORCID 0000-0002-6487-9339
Tian-Jun GongAnhui Province Key Laboratory of Biomass Chemistry, CAS Key Laboratory of Urban Pollutant Conversion, University of Science and Technology of China, Hefei 230026, China.ORCID 0000-0001-5484-8531

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aliphatic amines are ubiquitous core structural motifs in bioactive molecules including natural products, pharmaceuticals, and agrochemicals, driving ongoing demand for versatile, green, and practical synthetic strategies to construct complex aliphatic amines from inexpensive, readily available, structurally diverse feedstocks. Here, we report an iron-catalyzed decarboxylative carbonyl alkylative amination of aldehydes, amines, and carboxylic acids in HFIP under mild light irradiation at room temperature, with no additional additives and only CO

Identifiers

PMID42361183
PMCPMC13308601

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.