Evidence map›Paper›PMID 42360871›Full record

ArticleThe journal of physical chemistry letters2026

Detecting Vibrational Energy Transfer into an Enzyme Active Site via a Transition State Analog.

Jan Gerrit Löffler, Erhan Deniz, Yunxia Shen, Carolin Feid, Jens Bredenbeck

Abstract read
In one paragraph

Article in The journal of physical chemistry letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jan Gerrit LöfflerInstitute of Biophysics, Johann Wolfgang Goethe-University, Max-von-Laue-Straße 1, 60438 Frankfurt am Main, Germany.
Erhan DenizInstitute of Biophysics, Johann Wolfgang Goethe-University, Max-von-Laue-Straße 1, 60438 Frankfurt am Main, Germany.ORCID 0000-0002-6890-2989
Yunxia ShenInstitute of Biophysics, Johann Wolfgang Goethe-University, Max-von-Laue-Straße 1, 60438 Frankfurt am Main, Germany.
Carolin FeidInstitute of Biophysics, Johann Wolfgang Goethe-University, Max-von-Laue-Straße 1, 60438 Frankfurt am Main, Germany.
Jens BredenbeckInstitute of Biophysics, Johann Wolfgang Goethe-University, Max-von-Laue-Straße 1, 60438 Frankfurt am Main, Germany.ORCID 0000-0003-1929-9092

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vibrational energy transfer (VET) in enzymes has been discussed in the context of enzyme catalysis. A key point for experimentally investigating VET is to position suitable vibrational energy sensors in the delicate active sites of enzymes without disturbing their native state. Ideally, native substrates and/or inhibitors can be repurposed as vibrational energy sensors. Here, we demonstrate that the azide anion (N

Identifiers

PMID42360871
PMCPMC13592068

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.