ReviewCellular and molecular neurobiology2026
The Diagnostic and Therapeutic Value of Micro-RNA in Parkinson's Disease.
Review in Cellular and molecular neurobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
The pathogenesis of Parkinson's disease (PD) remains incompletely understood, and effective early diagnostic biomarkers and disease-modifying therapies are lacking. MicroRNAs (miRNAs), a class of small non-coding RNAs, have emerged as critical regulators of gene expression involved in key pathological processes of PD, including neuronal apoptosis, mitochondrial dysfunction, oxidative stress, and α-synuclein (α-syn) aggregation. Recent evidence suggests that dysregulated miRNAs expression contributes significantly to PD progression and may serve as minimally invasive biomarkers for early diagnosis. Furthermore, miRNA-based therapeutic strategies offer promising avenues for targeting disease-related molecular pathways. This review summarizes the mechanistic roles of miRNAs in PD pathogenesis and highlights their potential clinical applications in diagnosis and therapy.
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