Evidence map›Paper›PMID 42360616›Full record

ArticleTherapeutic innovation & regulatory science2026

Measuring Centralized Patient Outreach Recruitment Strategies and their Costs in Clinical Trials.

Jennifer Y Kim, Mary Jo Lamberti, Hana Do

Abstract read
PubMed Publisher
In one paragraph

Article in Therapeutic innovation & regulatory science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jennifer Y KimTufts Center for the Study of Drug Development (CSDD), Tufts School of Medicine, 145 Harrison Ave, Boston, MA, 02111, USA. Jennifer_y.kim@tufts.edu.
Mary Jo LambertiTufts Center for the Study of Drug Development (CSDD), Tufts School of Medicine, 145 Harrison Ave, Boston, MA, 02111, USA.
Hana DoTufts Center for the Study of Drug Development (CSDD), Tufts School of Medicine, 145 Harrison Ave, Boston, MA, 02111, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough patient recruitment is a major contributor to clinical trial costs, expenditures on centralized-sponsor-initiated patient outreach strategies-across therapeutic areas remain poorly characterized. Quantifying the specific outreach tactics and their expenditures is essential for optimizing resource allocation and effective planning.

methodsThe Tufts Center for the Study of Drug Development collected centralized patient outreach recruitment metrics and cost data from eight sponsor and contract research organizations across several major therapeutic areas, including oncology, central nervous system (CNS), and cardiovascular disease. Data gathered focused on study/protocol characteristics, study enrollment data, recruitment tactics, and budgetary items for 32 studies.

resultsAcross six therapeutic areas, the median budget for centralized patient outreach recruitment was $1,334,821.00. Social media, which included Facebook ads, Instagram, and Google ads was widely used across all studies, with an average allocation of 64.7% of the total centralized patient outreach recruitment budget. The median centralized outreach recruitment cost-per-patient ranged from $143 in vaccine studies to $11,392 in immunology studies.

Indexed as

Clinical Trials as TopicPatient SelectionBudgetsHumansSocial MediaCentralized recruitmentpatient recruitment budgetpatient recruitment cost dataSponsor-initiated outreach

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.