Evidence map›Paper›PMID 42360581›Full record

ArticleJournal of cancer survivorship : research and practice2026

Development of a clinical decision support system for exercise prescription among cancer survivors: a modified Delphi study.

Anastasios Manettas, Kristin L Campbell, Maria Charalampopoulou, Nicola Greco, Joachim Wiskemann, Panagiotis Tsaklis, Lidwine Mokkink

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Article in Journal of cancer survivorship : research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anastasios ManettasDepartment of Physiotherapy and Occupational Therapy, University Hospital Zurich, 8091, Zurich, Switzerland. anastasios.manettas@usz.ch.
Kristin L CampbellDepartment of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Maria CharalampopoulouFirst Department of Propaedeutic Surgery, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Nicola GrecoDepartment of Physiotherapy and Occupational Therapy, University Hospital Zurich, 8091, Zurich, Switzerland.
Joachim WiskemannDivision of Medical Oncology, University Clinic Heidelberg and National Center for Tumor Diseases (NCT) Heidelberg, a partnership between DKFZ and University Medical Center Heidelberg, Im Neuenheimer Feld 460, Heidelberg, 69120, Germany.
Panagiotis TsaklisBiomechanics and Ergonomics, ErgoMech Laboratory, Department of Physical Education and Sport Science, University of Thessaly, 42100, Trikala, Greece.
Lidwine MokkinkEpidemiology and Data Science, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeExercise is safe and beneficial for cancer survivors, with evidence-based guidelines supporting its use to improve health-related outcomes. However, access to structured exercise oncology programs remains limited, and available services are typically accessible only for individuals living near major health care centers. The aim of this study was to develop the content and layout of a clinical decision support system (CDSS) that enables the delivery of evidence-based, personalized exercise prescriptions for cancer survivors across a nationwide network of health care institutions in Switzerland.

methodsA Delphi study involving a diverse panel of clinical experts, including exercise physiologists, oncologists, physiotherapists, and researchers, was conducted. The study was informed by a scoping review of randomized controlled trials in exercise oncology. The participants rated and refined proposals regarding the layout and key components of a CDSS for exercise oncology across three rounds. Consensus was defined as at least 67% agreement among the participants.

resultsThe Delphi process resulted in the content and layout comprising a measurement set, personalizable exercise prescriptions, SMART goal standardization, and structured safety considerations. Key elements included the integration of progression and overload principles alongside Frequency-Intensity-Time-Type (FITT) criteria and the use of validated patient-reported outcome measures (PROMs) along with additional functional and fitness-related outcomes.

conclusionThe content and layout of a CDSS for evidence-based prescriptions in exercise oncology was developed in this study. This CDSS bridges the gap between published evidence and real-world practice, equipping health professionals across Switzerland with a practical tool to deliver safe, effective, and individualized exercise interventions for cancer survivors. IMPLICATIONS FOR CANCER SURVIVORS: Implementing this CDSS can improve access to consistent, evidence-based exercise oncology services and help reduce geographic disparities for survivors living in rural and other peripheral regions.

Indexed as

Cancer survivorCDSSExerciseOncologyPrescriptionRehabilitation

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.