ArticleJACC. Case reports2026
Nausea, Fatigue, and T-Wave Inversion: An Electrocardiographic Challenge.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
case summaryIn adults, T-wave inversion on the 12-lead electrocardiogram (ECG) often raises suspicion for ischemia. However, in young adults, other potential etiologies become more likely. We present the case of an 18-year-old woman with a history of depression who presented to the emergency department with nausea, fatigue, and tremulousness. The ECG revealed precordial T-wave inversions. TAKE-HOME MESSAGES: Lithium competitively inhibits channels and pumps that control both slow-response action potentials (sinoatrial, atrioventricular nodal cells), and fast-response action potentials (Purkinje fibers, cardiomyocytes). As such, lithium intoxication can present with a wide spectrum of ECG abnormalities, most commonly T-wave inversion and QT prolongation.
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