Evidence map›Paper›PMID 42359759›Full record

ReviewRadiology and oncology2026

Tumor ablation: emerging uses, challenges, and strategic implementation. A green paper by the Network of Expertise in Cancer (JANE-2), High Tech Medical Resources, network on Physical Methods of Tumor Ablation.

Julie Gehl, Philippe L Pereira, Colin P Cantwell, Frédéric Deschamps, Anja Kocijancic, Nina Schmidt, Rok Dezman, Greta Chlebopasevienė, Andrei Roman, Maja Cemazar and 1 more

Abstract readReview
In one paragraph

Review in Radiology and oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Julie Gehl1Department of Clinical Oncology and Palliative Care, Zealand University Hospital, Roskilde, Denmark.
Philippe L Pereira3Center of Radiology, Minimally Invasive Therapies and Nuclear Medicine, SLK-Kliniken GmbH, Heilbronn, University of Heidelberg and University of Tübingen, Heilbronn, Germany.
Colin P Cantwell4Department of Radiology and University College Dublin, St. Vincent's University Hospital, Dublin, Ireland.
Frédéric Deschamps5Gustave Roussy, Departement Anesthésie, Chirurgie et Interventionnel (DACI), Service de Radiologie Interventionnelle, Villejuif, France.
Anja Kocijancic6Institute of Oncology Ljubljana, Ljubljana, Slovenia.
Nina Schmidt1Department of Clinical Oncology and Palliative Care, Zealand University Hospital, Roskilde, Denmark.
Rok Dezman7Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Greta Chlebopasevienė9Department of Oncology and Hematology, Lithuanian University of Health Sciences Hospital, Kaunas Clinics, Kaunas, Lithuania.
Andrei Roman10Department of Radiology, The Oncology Institute "Prof. Dr. Ion Chiricuţă" Cluj-Napoca, Cluj-Napoca, Romania.
Maja Cemazar6Institute of Oncology Ljubljana, Ljubljana, Slovenia.
Gregor Sersa6Institute of Oncology Ljubljana, Ljubljana, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of oncology has witnessed remarkable progress with the integration of high-tech innovations in tumor ablation. Tumor ablation therapies, such as radiofrequency ablation (RFA), microwave ablation (MWA), cryoablation (Cryo), irreversible electroporation (IRE), and electrochemotherapy (ECT) have evolved beyond conventional boundaries, offering patients less invasive, highly targeted therapeutic options. Since it works across cancer histologies, tumor ablation is being integrated into cancer care at several levels. Tumor ablation is even considered curative in selected patients with small primary or secondary tumors, e.g. in the liver. Furthermore, it is central in treatment of oligometastatic disease or oligoprogression. Finally, ablation is widely used for symptomatic relief when tumors lead to symptoms affecting quality of life. Knowledge about ablative therapies and their inclusion at multidisciplinary team decision making enables effective and more personalized treatment for patients. This review synthesizes emerging applications of these therapies, focusing on artificial intelligence-driven personalization, robotic-assisted precision, and hybrid models combining ablation with systemic treatments, immunotherapy or targeted drug delivery. It also discusses the infrastructural, educational, regulatory, and ethical challenges that influence the clinical adoption of such treatments. Finally, the review presents strategic recommendations for integrating advanced ablation therapies into healthcare systems while ensuring equity, patient trust, and global accessibility.

Indexed as

Ablation TechniquesNeoplasmsArtificial IntelligenceCatheter AblationCryosurgeryElectrochemotherapyHumansRadiofrequency Ablationcancer ablationemerging applicationsethical issueshigh-tech innovationsregulatory issues

Identifiers

PMID42359759
PMCPMC13307015

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.