Evidence map›Paper›PMID 42359548›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2026

Population-based prevalence and screening gaps of hepatitis C, B and D, Germany, 2020 to 2021.

Zahra Ghodratian, Katharina Grikscheit, Loraine Busetto, Benjamin Marx, Niko Kohmer, Arne Auste, Raphael Scheu, Manuela Harries, Vanessa Melhorn, Thomas Illig and 4 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Zahra GhodratianInstitute for Medical Virology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany.
Katharina GrikscheitInstitute for Medical Virology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany.
Loraine BusettoInstitute for Medical Virology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany.
Benjamin MarxInstitute for Medical Virology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany.
Niko KohmerInstitute for Medical Virology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany.
Arne AusteInstitute for Medical Virology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany.
Raphael ScheuInstitute for Medical Virology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany.
Manuela HarriesHelmholtz Centre for Infection Research, Department of Epidemiology, Braunschweig, Germany.
Vanessa MelhornHelmholtz Centre for Infection Research, Department of Epidemiology, Braunschweig, Germany.
Thomas IlligHannover Unified Biobank, Hannover Medical School, Hannover, Germany.
Monika StrengertHelmholtz Centre for Infection Research, Department of Epidemiology, Braunschweig, Germany.
Annemarie BergerInstitute for Medical Virology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany.
Berit LangeHelmholtz Centre for Infection Research, Department of Epidemiology, Braunschweig, Germany.
Sandra CiesekInstitute for Medical Virology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUNDChronic hepatitis C (HCV) and hepatitis B (HBV) viruses remain major causes of liver-related morbidity and mortality. Despite a low prevalence in Germany, migration from higher-endemic regions and screening gaps may hinder progress towards World Health Organization (WHO) 2030 elimination targets. Population-based data are needed for surveillance, screening and elimination.AIMWe aimed to estimate prevalence of HCV, HBV and hepatitis D virus (HDV) in adults in Germany.METHODSWe retrospectively analysed 10,000 serum samples from the Multilocal and Serial Prevalence Study of Antibodies against SARS-CoV-2 in Germany (MuSPAD, 2020-2021), by age and gender distribution. Samples were pooled and tested for HCV and HBV by PCR, for HBV surface antigen (HBsAg) and for antibodies against HCV and HBV. Samples positive for HBsAg were analysed for HDV.RESULTSActive HCV infection (HCV RNA) was detected in four (0.04%; 95% CI: 0.02-0.1) persons. Seroprevalence for HCV was 0.17% (95% CI: 0.11-0.27), highest among 60-69-year-olds (0.53%). Active HBV infection (HBV DNA and/or HBsAg) was detected in 21 participants (0.21%; 95% confidence interval (CI): 0.14-0.32), peaking at 0.44% among 30-39-year-olds. No HDV infection was confirmed.CONCLUSIONRecognising that relevant high-risk groups may be underrepresented in our data, the overall HCV and HBV prevalence in Germany appears low but non-negligible. Adults under 35 years are not covered by the national health check programme for all adults aged ≥ 35 years, suggesting potential screening gaps. Systematic HDV testing among HBV-positive individuals and targeted testing strategies may support progress towards WHO elimination goals.

Indexed as

HepacivirusHepatitis BHepatitis CHepatitis DMass ScreeningAdolescentAdultAgedFemaleGermanyHepatitis B Surface AntigensHepatitis B virusHepatitis C AntibodiesHepatitis Delta VirusHumansMaleHepatitis B Surface AntigensHepatitis C AntibodiesepidemiologyHepatitis B virusHepatitis C virusscreeningviral hepatitis

Identifiers

PMID42359548
PMCPMC13309759

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.