Evidence map›Paper›PMID 42359373›Full record

ArticleDental research journal2026

Investigating the effect of casein phosphopeptide-amorphous calcium phosphate, fluoride varnish, and diode laser on enamel microhardness.

Haleh Hali, Razieh Mahmoudi, Parastoo Namdar, Abolfazl Hosseinnataj, Alireza Sedighi

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In one paragraph

Article in Dental research journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haleh HaliDepartment of Pediatric Dentistry, Dental Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Razieh MahmoudiDental Research Center, Student Research Committee, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.
Parastoo NamdarDepartment of Orthodontics, Dental Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Abolfazl HosseinnatajDepartment of Biostatistics, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.
Alireza SedighiDental Research Center, Student Research Committee, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Laser therapy with fluoride-containing material, such as casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), is a new technique for caries prevention. The purpose of this study is to investigate the effect of CPP-ACP, fluoride varnish (FV), and diode laser (DL) on the microhardness of enamel. Materials and Methods: This Results: The mean microhardness of all teeth was significantly changed after the intervention ( Conclusion: Using DL along with FV or GCTM can have a synergic effect on the amount of microhardness. Although this effect was not observed in the DL + MIPP group, FV has a positive effect on tooth microhardness.

Indexed as

Casein phosphopeptide-amorphous calcium phosphatediodefluoridelasermicrohardness

Identifiers

PMID42359373
PMCPMC13293544

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.