Evidence map›Paper›PMID 42359336›Full record

ArticleBreast cancer (Dove Medical Press)2026

Risk Factors and Prognosis Analysis of Infiltrating Micropapillary Carcinoma of Breast: A Retrospective Study.

Pengfei He, Yupeng Sha, Yige Lu, Tong Li, Xiaoming Li, Yixin Liu, Hui Pang, Jiguang Han, Quan Yuan

Abstract read
In one paragraph

Article in Breast cancer (Dove Medical Press), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pengfei He *Department of Breast Surgery, Nanyang Second People's Hospital, Nanyang, Henan, People's Republic of China.
Yupeng Sha *Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, People's Republic of China.
Yige Lu *Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, People's Republic of China.
Tong LiHarbin Medical University Cancer Hospital, Harbin, Heilongjiang, People's Republic of China.
Xiaoming LiHarbin Medical University Cancer Hospital, Harbin, Heilongjiang, People's Republic of China.
Yixin LiuHarbin Medical University Cancer Hospital, Harbin, Heilongjiang, People's Republic of China.
Hui PangHarbin Medical University Cancer Hospital, Harbin, Heilongjiang, People's Republic of China.
Jiguang HanHarbin Medical University Cancer Hospital, Harbin, Heilongjiang, People's Republic of China.ORCID 0000-0002-5973-2842
Quan YuanHarbin Medical University Cancer Hospital, Harbin, Heilongjiang, People's Republic of China.ORCID 0009-0003-8060-2158

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Invasive micropapillary carcinoma (IMPC) is a rare breast cancer subtype with high invasiveness and lymphovascular/lymph node metastasis. While poor prognosis is reported, long-term survival and roles of molecular subtyping/laboratory markers remain unclear. Methods: We retrospectively analyzed 653 IMPC patients from a Chinese center (as of December 2024). Kaplan-Meier estimated progression-free survival (PFS) and overall survival (OS); Cox regression assessed prognostic factors. Results: Among 653 patients with IMPC, the molecular subtype distribution was as follows: HR+/HER2-, 48.2%; HR+/HER2+, 35.4%; HR-/HER2-, 11.0%; and HR-/HER2+, 5.4%. Most patients had T1-2 disease and were postmenopausal. The 3-year and 5-year OS rates were 97.42% and 93.73%, respectively, while the 3-year and 5-year PFS rates were 90.66% and 81.20%, respectively. Kaplan-Meier analysis showed significant differences in PFS among molecular subtypes, but not in OS. In multivariable analysis, the HR+/HER2+ subtype and higher total bilirubin were independently associated with better PFS, whereas higher systemic immune-inflammation index and stage IIIB were associated with worse PFS. Poorer OS was independently associated with advanced stage, no surgery, alcohol consumption history, higher systemic immune-inflammation index, menopausal status, and elevated blood glucose, while mastectomy and endocrine therapy were associated with better OS. Conclusion: IMPC shows favorable OS but requires progression risk monitoring. PFS varied by molecular subtype, while OS did not. Molecular typing, clinical stage, and inflammatory/biochemical markers aid prognosis and personalized treatment.

Indexed as

breast cancerinvasive micropapillary carcinomaoverall survivalprognostic factorsprogression-free survival

Identifiers

PMID42359336
PMCPMC13291655

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.