SynthesisFrontiers in medicine2026
Autohemotherapy combined with other external treatments of Traditional Chinese Medicine for chronic urticaria: a systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Background: Chronic urticaria (CU) is a refractory, recurrent skin disease that adversely affects patients' quality of life, mental health. Autohemotherapy (AHT) and various external treatments of Traditional Chinese Medicine (TCM) are reported to be effective in improving CU with few side effects. This study aims to evaluate the efficacy and safety of AHT combined with various TCM external treatments for CU. Methods: This study was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. 11 Chinese and English databases were searched from database inception to August 10, 2025, for randomized controlled trials (RCTs) on AHT combined with other TCM external treatments for CU. Two researchers independently completed literature screening and data extraction. Study quality was evaluated using the Cochrane Risk of Bias Tool 2.0 (RoB 2.0). Meta-analysis was performed using STATA 18.0. Results: A total of 20 studies involving 1,461 participants were included. The intervention group received AHT combined with other TCM external treatments, and the control group received Western medicine. The overall response rate was significantly better in the intervention group (RR: 1.17; 95% Confidence Interval, CI: 1.10-1.24; Conclusion: Autohemotherapy combined with some other TCM external treatments can improve clinical efficacy and reduce recurrence rates. However, due to concerns regarding unclear randomization and blinding, diverse outcome measures, methodological limitations, and high clinical heterogeneity among the included studies, more rigorous prospective studies are needed to conclusively evaluate its efficacy and safety. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, CRD420261281760.
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