ArticleFrontiers in medicine2026
Comparison of Child-Pugh and MELD scores in predicting survival of hepatocellular carcinoma patients with splenomegaly undergoing TACE: a real-world study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aims to compare the predictive value of Child-Pugh and MELD scores for the survival rate of HCC patients with splenomegaly who received TACE. Methods: From January 2018 to January 2025, 306 patients with splenomegaly and HCC who underwent TACE treatment at a tertiary hospital were included in the study. Patients were divided into groups A ( Results: The comparison analysis of baseline characteristics showed that there were statistically significant differences in age, maximum tumor diameter, proportion of multifocal tumors, spleen length, total bilirubin, albumin, international normalized ratio (INR), creatinine, red blood cell distribution width (RDW), platelet count, and the incidence of ascites and hepatic encephalopathy among different Child-Pugh grades (all Conclusion: In patients with HCC and splenomegaly, both Child-Pugh and MELD scores can effectively stratify prognosis. However, the MELD score showed superior predictive performance for 1-year survival rate after TACE, which is worthy of more attention in clinical prognosis assessment.
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