ArticleFrontiers in medicine2026
Oral whole-leaf matcha partially attenuates UV-induced dermoepidermal disruption and collagen phenotype alterations in a rat model of repeated photoaging.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Repeated ultraviolet (UV) exposure promotes oxidative stress, extracellular matrix remodeling, and disruption of dermoepidermal architecture, all of which contribute to skin photoaging. Although green tea derivatives have been investigated for photoprotective effects, the impact of oral whole-leaf matcha powder on cumulative UV-induced skin changes remains insufficiently characterized. The aim of this study was to investigate whether oral whole-leaf matcha powder was associated with attenuation of UV-induced dermoepidermal disruption, collagen phenotype alterations, and skin surface changes in a rat model of repeated UV exposure. Methods: Thirty-two female Sprague-Dawley rats were randomly assigned to Control, UV, Matcha, and UV + Matcha groups ( Results: Compared with controls, repeated UV exposure increased epidermal thickness ( Conclusion: Oral whole-leaf matcha powder was associated with partial attenuation of UV-induced phenotypic changes, including dermoepidermal structural alterations, collagen phenotype shifts, and surface deterioration, in this rat model of repeated photoaging. These findings suggest a potential adjunctive photoprotective effect, although further molecular-level validation and clinical studies are required to clarify the underlying pathways and translational relevance.
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