SynthesisFrontiers in immunology2026
Global research trends and hotspots in human immunodeficiency virus-associated cervical cancer (1990-2025): a multi-database bibliometric analysis.
Synthesis in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Research on cervical cancer among WLWH represents a critical area for advancing long-term prevention and clinical management strategies. Yet as the volume of published literature in this field continues to grow rapidly, synthesizing and appraising the available evidence in a comprehensive manner has become increasingly challenging. Objective: This study aims to map the global research landscape, identify leading contributors and collaborative networks, and delineate the knowledge base and emerging research priorities in HIV-associated cervical cancer through a bibliometric analysis of multiple databases. Particular attention is given to the molecular and immunological mechanisms underlying the synergistic oncogenic interaction between HIV and high-risk HPV, as well as current trends in translational clinical research. Methods: Publications on HIV and cervical cancer from January 1, 1990, to December 31, 2025 (n = 6,137) were retrieved and analyzed using bibliometric and visualization tools, including R (bibliometrix), Python, VOSviewer, and CiteSpace. Analyses encompassed publication trends, collaboration networks, keyword co-occurrence, and thematic evolution. Results: Research output has increased steadily, led by the United States, followed by China, South Africa, India, and the United Kingdom. The most productive journals include International Journal of Cancer and AIDS, which are also among the most frequently cited. The seminal reference is "Cancer-related Inflammation." Emerging research frontiers center on cervical cancer screening, WLWH, human papillomavirus vaccination, and deep learning. Conclusions: Future directions will likely emphasize lifecycle vaccination strategies for WLWH, precision therapies guided by the immune microenvironment, and scalable screening approaches for low-resource settings. These findings provide evidence-based insights to inform global health policy and accelerate cervical cancer elimination efforts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.