ArticleFrontiers in immunology2026
Immunomodulatory effects of synthetic antimicrobial peptides on LPS-induced inflammatory responses in THP-1 macrophages.
Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Macrophage polarization is critical for maintaining health and for recognizing and eliminating a diverse array of antigens. These disparate roles require distinct macrophage responses, and the induction of inappropriate macrophage responses is intimately associated with disease. It is therefore important to understand how macrophages respond to new biomedicines and to harness those with immune modulatory properties for therapeutic use. This study defines the effects of rationally designed antimicrobial peptides (AMPs) on macrophage polarization and function, compared with natural host-defense peptides (natural AMP LL-37 and antibiotic polymyxin B). Using an
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