ArticleParasite epidemiology and control2026
Molecular characterization of filarial infections and their associated risk factors in rural community of Southeastern Gabon.
Article in Parasite epidemiology and control, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Filarial infections continue to represent a considerable public health challenge in resource-limited communities in sub-Saharan Africa. In Gabon, the implementation of effective control strategies, such as mass drug administration (MDA), is hindered by a lack of contemporary data on the local distribution, molecular diversity, and associated risk factors of these infections, particularly in rural areas where Methods: A cross-sectional survey was conducted in August 2021 among 90 volunteers from Dienga, southeastern Gabon. Blood samples were analyzed by microscopy and quantitative PCR (qPCR) targeting the 28S rRNA gene and sequencing. Sociodemographic, clinical, and knowledge data were collected via standardized questionnaires. Statistical analyses employed chi-square tests and logistic regression. Results: The overall filarial qPCR (23.33%) prevalence was 1.75-fold higher than microscopy (13.33%), confirming the superior sensitivity of qPCR for detecting sub-microscopic infections. Conclusion: This study provides the first molecular evidence of a high prevalence of
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